15 citations,
February 2023 in “Colloids and surfaces. B, Biointerfaces” Smaller curcumin nanocrystals penetrate skin better, but additives and particle size affect absorption and accumulation.
January 2022 in “Advanced Pharmaceutical Bulletin” Clove oil and grape seed extract increase finasteride skin absorption, while urea decreases it.
22 citations,
April 2018 in “Pharmaceutics” New methods improve how well skin treatments work by helping drugs get through the skin barrier.
25 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
188 citations,
October 2012 in “The AAPS Journal” The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Carthamus tinctorius floret extract is a safe hair growth promoter with good skin absorption.
November 2005 in “CRC Press eBooks” SEPA 0009 is a promising and safe skin penetration enhancer for topical use.
26 citations,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.
12 citations,
March 2020 in “Journal of Bioactive and Compatible Polymers” Nanoparticles show potential for controlled release of hair loss drugs, improving treatment effectiveness.
3 citations,
September 1989 in “Journal of Investigative Dermatology” Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.
82 citations,
May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
3 citations,
April 2015 in “International research journal of pharmacy” Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
5 citations,
February 2010 in “Drug development and industrial pharmacy” Vesicles made of behenyltrimethylammonium chloride and stearic acid can triple the skin absorption of hinokitiol, which may help with hair growth.
January 2024 in “RSC pharmaceutics” Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.
23 citations,
June 2014 in “Journal of Pharmaceutical Sciences” Finasteride cream helps hair growth with less side effects.
268 citations,
April 2009 in “International Journal of Pharmaceutics” Niosomes improve minoxidil skin delivery for hair loss treatment.
18 citations,
March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
72 citations,
December 2012 in “Expert Opinion on Drug Delivery” Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
34 citations,
October 1994 in “Journal of Pharmaceutical Sciences” Ethanol over 50% helps minoxidil absorb better into skin.
August 2022 in “Scholars academic journal of pharmacy” Invasomes loaded with clotrimazole gel could improve drug delivery through the skin for fungal treatment.
6 citations,
December 2015 in “International journal of nanomedicine” Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.
55 citations,
June 2013 in “Dermatologic Surgery” Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
1 citations,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
140 citations,
December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
10 citations,
February 2021 in “International Journal of Nanomedicine” Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.
2 citations,
July 2022 in “BioMed Research International” Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.
1 citations,
February 2023 in “Applied sciences” The new topical growth hormone formula has high skin penetration and bioavailability.
181 citations,
July 2004 in “Journal of controlled release” Smaller nanoparticles improve minoxidil absorption through hair follicles.
8 citations,
January 2019 in “Nanomedicine” Egyptian researchers are advancing in pharmaceutical nanotechnology, potentially improving health outcomes and the economy.