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Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Understanding the mouse hair cycle is crucial for cancer research.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Wool follicles are complex, involving interactions between different cell types and structures.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Neurosteroids show promise for treating epilepsy and more research is needed.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

These skin conditions in African men need combined medical treatments and lifestyle changes.

New treatments for acne scars are safer and more effective because we understand the causes better.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.