research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
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research Next-Generation Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research TGFβ Family Mimetic Peptide Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice
A peptide called DPS-1 helps human scalp cells grow and stimulates hair growth in mice.
research Significant Effects of Mild Endogenous Hormonal Changes in Humans: Considerations for Low-Dose Testing
Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
research Repurposing of Various Current Medicines as Radioprotective Agents
Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.
research Hair Follicle-Derived IL-7 and IL-15 Mediate Skin-Resident Memory T Cell Homeostasis and Lymphoma
Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases
Exosomes could be effective for improving skin health and treating skin diseases.
research Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways
Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.
research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
Creating fully functional artificial skin for chronic wounds is still very challenging.
research Beta-Catenin-Mediated Hair Growth Induction Effect of 3,4,5-Tri-O-Caffeoylquinic Acid
3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.
research Cyproterone Acetate: A Genotoxic Carcinogen?
Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
research Significant Effects of Mild Endogenous Hormonal Changes in Humans: Considerations for Low-Dose Testing
Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Activity
SHED-CM can reduce hair graying and protect against damage from X-rays.
research Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis
Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.
research Regulation of Masculinization: Androgen Signaling for External Genitalia Development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Adipokines in the Skin and Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Low-Level Pulsed Wave Red Light Induces Type I Procollagen Protein and ATP Production at Shorter Treatment Times Compared to Continuous Wave Red Light
Pulsed red light boosts collagen and energy in cells faster than continuous red light.
research Family Planning 2011: Better Use of Existing Methods, New Strategies, and More Informed Choices for Female Contraception
The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.
research Hair Analysis in Health Assessment
Hair mineral analysis might help diagnose diseases early, but standard methods are needed.
research Australian Hair and Wool Research Society Cutaneous Biology and Endocrinology Workshop
The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
research Plants Used in Cosmetics
Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
research Two-Photon Microscopy for Intracutaneous Imaging of Stem Cell Activity in Mice
Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
research Hair Removal Using a Pulsed-Intense Light Source
Pulsed-intense light can significantly reduce hair, with effectiveness depending on treatment number and timing, and has mild side effects.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.