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Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.

Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

Some herbs show promise as antiandrogenic agents.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

New compounds may soon be tested to treat excessive hair growth in women.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Different lasers and radiofrequency affect skin differently, important for dermatologists to choose the right treatment.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Sinapic acid may help hair growth by activating a specific cell pathway.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.

Phototrichogram and hair diameter measurements are effective, noninvasive ways to assess hair growth and detect early hair loss, with the most common pattern being reduced hair density.

Taking too many vitamin and mineral supplements can cause serious health problems.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

Finasteride cream helps hair growth with less side effects.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.