2 citations
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January 1996 in “Annals of saudi medicine/Annals of Saudi medicine” This study found that severe forms of alopecia areata may be associated with poor treatment response, particularly in cases with extensive hair loss, juvenile onset, or nail changes.
1 citations
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October 2020 in “International Journal of Research in Dermatology” This study found that short vellus hair and yellow dots are common dermoscopic findings in alopecia areata, with variations indicating disease activity or remission.
1 citations
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October 2020 in “Nepal journal of dermatology, venereology & leprology” This study found that patients on maintenance hemodialysis commonly experience cutaneous symptoms, with pigmentation and nail disorders being the most prevalent.
August 2025 in “Medical Journal of Armed Police Force Nepal” This study found that alopecia areata was more common in males, most frequently appeared on the scalp, and typically presented as patchy hair loss.
May 2023 in “Advanced medical journal” In this study, researchers found that hair changes, particularly anagen effluvium, were the most common mucocutaneous side effects in cancer patients undergoing chemotherapy, occurring in 31.71% of cases, followed by skin, nail, and mucosal changes, highlighting the morbidity associated with antineoplastic drug side effects.
May 2023 in “Dermatology Reports” In this original study, researchers documented 121 COVID-19 cases with a wide range of mucocutaneous manifestations, some linked to internal organ damage and others to new vaccine-associated dermatoses, emphasizing the importance of rapid diagnosis to prevent potentially life-threatening systemic events.
May 2023 in “Clinical and Experimental Dermatology” Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.
February 2023 in “Journal of vaccines and immunology” This article reviews the clinical features and potential associated conditions of alopecia areata, including its progression and histopathological characteristics, but reports no new clinical findings.
October 2019 in “Journal of Evolution of Medical and Dental Sciences” This case report describes a 56-year-old male with chronic watery diarrhea, hyperpigmentation, and alopecia, in whom colonoscopy revealed multiple polypoidal lesions from the distal transverse colon to the rectum.
August 2019 in “Reactions Weekly” Daclizumab may cause psoriasis-like skin problems in multiple sclerosis patients.
January 2015 in “Indian Dermatology Online Journal” This diagnostic discussion reports that diffuse alopecia areata was identified in a patient with diffuse hair loss, based on specific histopathological features observed in a biopsy.
January 2014 in “Progress of Digestive Endoscopy” This case report describes a 60-year-old woman with Cronkhite-Canada syndrome whose symptoms and polyposis improved following prednisolone therapy, but emphasizes the need for periodic digestive tract screening due to associated cancer risks.
October 2012 in “CRC Press eBooks” This abstract describes various hair and nail changes associated with HIV infection, highlighting telogen effluvium and onychomycosis as common manifestations, while noting that treatment for onychomycosis does not differ between HIV-infected and non-infected individuals.
January 2009 in “Beijing Medical Journal” This study found that combined therapy, including oral and topical treatments, was effective in improving severe alopecia areata, with injection site pain and facial hair changes as common side effects.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This paper reviews the diverse skin, nail, and hair changes caused by medications, highlighting hyperpigmentation, alopecia, and nail structural alterations, but reports no new data.
25 citations
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January 2011 in “Annals of Dermatology” This case report documents a 61-year-old woman treated with erlotinib who experienced the rare side effect of cicatricial alopecia.
6 citations
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March 2020 in “Anais Brasileiros de Dermatologia” This report highlights the successful treatment of skin and nail manifestations in a patient with primary hypothyroidism using levothyroxine, emphasizing the role of cutaneous symptoms in identifying thyroid disease.
5 citations
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January 2022 in “Journal of Cosmetic Dermatology” This review summarizes documented cases of hair and ungual changes associated with COVID-19, which may help to further understand the disease's clinical implications.
January 2026 in “Clinical & Translational Oncology” This expert consensus statement highlights that while targeted cancer therapies significantly improve patient survival, they often result in various skin toxicities, underscoring the need for early diagnosis, management, and multidisciplinary care to maintain patients' quality of life and ensure treatment continuity.
January 2022 in “IAR Journal of Parasitology & Infectious Disease” This study observed that 30.1% of older adults had nail changes, predominantly affecting the lower limbs, and hair disorders were less common, with alopecia being the only type recorded.
79 citations
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April 1996 in “JAMA” This article describes a case of selenium poisoning in a 36-year-old man who experienced hair loss, nail changes, and paresthesias after taking selenium-containing vitamin tablets.
29 citations
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January 2012 in “Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy” This review discusses the various skin, mucosa, and adnexa side effects associated with different chemotherapeutic agents and provides insights into their clinical presentation and management; it reports no new results.
August 2024 in “Journal of the American Academy of Dermatology” Nail color change might be an early sign of skin pigmentation from minocycline.
19 citations
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January 2018 Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.
2 citations
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June 2024 in “Journal of Clinical Medicine” This study identifies various nail changes in alopecia areata, which can affect quality of life, and suggests that while spontaneous improvement is possible, further research is needed to refine treatment strategies.
9 citations
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April 2018 in “Journal of Dermatological Treatment” This study found that oral tofacitinib monotherapy improved nail changes in 73.3% of adults with moderate-to-severe alopecia areata over a median period of 5 months, but nail improvement was not linked to the severity of hair loss or hair regrowth.
January 2026 in “Dermatology Practical & Conceptual” This study observed that 78.3% of patients with alopecia areata exhibited nail changes detectable by dermoscopy, notably nail pitting, in contrast to 14.2% of healthy controls, with these changes significantly associated with disease severity, age, and duration.
June 2025 in “British Journal of Dermatology” In this case study, nail changes and skin lesions helped diagnose a 60-year-old man with advanced cardiac amyloidosis, highlighting the importance of considering amyloidosis in differential diagnoses for similar nail abnormalities and assessing for systemic involvement.
January 2025 in “International Journal of Dermatology Sciences” In this study, nail changes, particularly pitting, were associated with moderate to severe cases of alopecia areata and a positive family history, highlighting potential genetic factors in the condition.
This study found that hair and nails can effectively measure hormone changes such as testosterone, estrogen, and progesterone during the peripubertal period in dogs, with variations observed between males and females at specific developmental stages.