research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
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330-360 / 1000+ results research Is Age at Puberty Associated with Semen Quality and Reproductive Hormones in Young Adult Life?
Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.
research Origanum Vulgare L. Leaves Extract Alleviates Testis And Sperm Damages Induced By Finasteride: Biochemical, Immunohistological And Apoptosis Genes Based Evidences
Oregano extract helps fix testis and sperm damage caused by finasteride.
research The Hydroxypropyl-β-Cyclodextrin-Minoxidil Inclusion Complex Improves the Cardiovascular and Proliferative Adverse Effects of Minoxidil in Male Rats: Implications in the Treatment of Alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research The 3D Bioprinted Scaffolds for Wound Healing
3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
research Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632
A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin
Special particles from skin cells can promote hair growth by activating a specific growth signal.
research Heat Enhanced Follicular Delivery of Isotretinoin to the Skin
Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.
research Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implications of Post-Translational Modifications
New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
research The Circular RNA circNlgn Mediates Doxorubicin-Induced Cardiac Remodeling and Fibrosis
A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.
research Larvicidal Potential, Antimicrobial Properties and Molecular Docking Analysis of Egyptian Mint (Mentha Rotundifolia) Against Culex Pipiens L. (Diptera: Culicidae) and Midgut-Borne Staphylococcus Aureus
Egyptian Mint effectively kills mosquito larvae and inhibits certain bacteria.
research Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells
Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
research The Rho Guanosine Nucleotide Exchange Factors Vav2 And Vav3 Modulate Epidermal Stem Cell Function
Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
research Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds
Transglutaminase activity is important for skin and is found in both mammals and birds.
research Effects of Non-Contingent Cocaine on 3alpha-Androstanediol: Disruption of Male Sexual Behavior
Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
DA-9401 helps protect rat testis from finasteride damage.
research Effect of Finasteride Particle Size Reduction on Its Pharmacokinetic, Tissue Distribution, and Cellular Permeation
Smaller finasteride particles increase effectiveness in treating hair loss.
research Transdermal Delivery of Minoxidil Using HA-PLGA Nanoparticles for the Treatment of Alopecia
Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.
research In Vitro and In Vivo Skin Distribution of 5α-Reductase Inhibitors Loaded Into Liquid Crystalline Nanoparticles
Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
research Skin Deposition and Permeation of Finasteride In Vitro: Effects of Propylene Glycol, Ethanol, and Sodium Lauryl Sulfate
Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
research MicroRNA-205 Promotes Hair Regeneration by Modulating Mechanical Properties of Hair Follicle Stem Cells
MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
research The Effect of Glycyrrhizic Acid and Aqueous Licorice Extract on Hair Growth Retardation: In Vitro Mechanistic and Efficacy Studies in Human
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability
Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
research A New Hair Follicle-Derived Human Epidermal Model for the Evaluation of Sunscreen Genoprotection
The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Topical Application of Aprepitant Inhibits Erlotinib-Induced Facial Dermatitis and Hair Loss
Topical aprepitant reduces skin rash and hair loss caused by cancer treatment.
research Development of Novel Wound Dressing Based on Elastin-Like Recombinamers for Skin Regeneration
Elastin-like recombinamers show promise for better wound healing and skin regeneration.