47 citations,
December 2011 in “Experimental Dermatology” CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.
April 2023 in “Journal of Investigative Dermatology” CGRP MAbs treatment for migraines may also improve rosacea symptoms, but more research is needed to confirm its effectiveness and safety.
66 citations,
July 2007 in “Journal of Molecular Medicine” Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
41 citations,
April 2009 in “Journal of comparative neurology” P2X3-IR fibers are widespread in rat skin and likely help detect pain.
32 citations,
February 2024 in “Growth Hormone & IGF Research” Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
29 citations,
March 2011 in “The Journal of Nutritional Biochemistry” Eating isoflavone can help mice grow hair by increasing a growth factor.
23 citations,
December 2008 in “Current medicinal chemistry” Stimulating sensory neurons can increase IGF-I production, which may help treat various diseases and improve tissue health.
13 citations,
December 2012 in “Frontiers in bioscience” Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
3 citations,
August 2018 in “Deleted Journal” Guasha changed rat skin appearance and blood vessels temporarily without affecting certain nerve proteins or fiber structure.
1 citations,
March 2012 in “Journal of the American Academy of Dermatology” Botulinum toxin A injections may help treat difficult cases of total hair loss.
January 2023 in “Л.Н. Гумилев атындағы Еуразия ұлттық университетінің хабаршысы” Botulinum toxin is effectively used to treat various painful conditions and its therapeutic uses are growing.
January 2016 in “프로그램북(구 초록집)” Hormones and neuropeptides affect hair growth, with androgens having opposite effects on beard and scalp hair.
August 2006 in “Experimental dermatology” Human scalp hair follicles can produce and respond to several hormones, affecting hair growth and pigmentation.
April 2023 in “Journal of The American Academy of Dermatology” Some drugs linked to growth hormones may increase the chance of hair loss in women.
185 citations,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
101 citations,
January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
75 citations,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
39 citations,
August 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
17 citations,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.
3 citations,
July 2013 in “Bioscience, Biotechnology, and Biochemistry” Chinese black tea extract helped mice grow hair, especially when combined with capsaicin.
April 2024 in “Deleted Journal” Scalp pain should be classified as a type of headache.
January 2022 in “Journal of Skin and Stem Cell” Trichodynia is a painful scalp condition needing targeted treatments beyond symptom management.
April 2017 in “InTech eBooks” Many people with hair loss experience scalp pain known as trichodynia, but the causes are unclear and treatments vary.
421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
396 citations,
May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
375 citations,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
306 citations,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
232 citations,
January 2013 in “Nature Cell Biology” Understanding where cancer cells come from helps create better prevention and treatment methods.
210 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
194 citations,
March 2003 in “American Journal of Pathology” Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.