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Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.

Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.

Genetic defects and UV radiation cause skin damage and aging.

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.

The document reports unique growth lines in a child after Stevens-Johnson syndrome, skin reaction from parsnips and sun in a girl, and itchy skin with xanthomas in a boy with Alagille syndrome.

Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.

Hair changes could indicate neurological diseases and help monitor treatment.

Meshushit ointment helps form thicker healing tissue and preserves hair follicles in burns.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Human skin can make serotonin and melatonin.

Fat cells help recruit healing cells and build skin structure during wound healing.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.