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480-510 / 1000+ resultsresearch Dermal lymphatic dilation in a mouse model of alopecia areata
In mouse models of alopecia areata, this study found increased dilation of lymphatic vessels in affected mice, with associated changes in gene expression related to vascular growth and immune cell movement.
research The Effectiveness of Cerium Oxide Nanoparticle-Based Drugs in Wound Healing in Animal Models
This review reports that cerium oxide nanoparticles may accelerate wound healing in animal models, but further standardized and comparative studies are needed to confirm their potential for clinical applications.
research Three-Dimensional Bioprinting Techniques in Skin Regeneration: Current Insights and Future Perspectives
This review highlights advancements in 3D bioprinting for skin tissue engineering, focusing on exosome-loaded bioinks that show potential for enhancing skin regeneration and repair.
research Evo Devo of the Vertebrates Integument
In this study, researchers propose that different vertebrate skin appendages, such as hair, feathers, and scales, evolved in parallel from a shared ancestral cell structure associated with teeth, dating back approximately 420 million years ago.
research Scarring Alopecias: Pathology and an Update on Digital Developments
This review discusses the challenges in diagnosing primary cicatricial alopecias and explores how improved communication and digital pathology could enhance diagnosis, but it reports no new clinical results.
research Impacts of iron on phosphate starvation-induced root hair growth in Arabidopsis
This study found that iron availability influences root hair growth under phosphate starvation by affecting auxin distribution, phosphate starvation-responsive genes, and vesicle trafficking.
research Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review
This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.
research Enhancing Skin Anti-Aging through Healthy Lifestyle Factors
This narrative review concluded that lifestyle factors such as nutrition, sleep, exercise, and social interactions play key roles in improving skin health and well-being with aging, and suggests social media campaigns could promote beneficial lifestyle changes in the future.
research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
This article reviews the immunometabolic mechanisms linking polycystic ovary syndrome to infertility and stresses the need for interdisciplinary approaches to treat PCOS-related fertility issues; it reports no new clinical results.
research Exploring the landscape of long COVID: prevalence and associated factors in patients assisted by a telehealth service
According to this study, nearly one-third of the participants experienced Long COVID, highlighting ongoing concerns about the disease's long-term implications despite the pandemic being under control.
research Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing
This study systematically reviews the development and applications of drug-loaded nanofiber scaffolds in wound healing, highlighting challenges such as maintaining drug activity and achieving controlled release, while summarizing preparation methods and describing advanced drug delivery schemes.
research Exosomes in stroke management: A promising paradigm shift in stroke therapy
This research review highlights the potential of exosome therapy to transform stroke treatment, reporting that in animal models, exosomes can reduce neuroinflammation, oxidative stress, and cell death, while promoting brain repair and regeneration. However, more evidence is needed before clinical applications in humans are established.
research Machine learning for nanozyme development in anti‐inflammatory applications
This review consolidates various rational design strategies for nanozymes, emphasizing the mechanisms needed for precise design and exploring their applications in treating inflammatory diseases, diagnosing diseases, and environmental uses, while also discussing the challenges and future prospects in this emerging field.
research Natural Compounds Targeting MAPK, PI3K/Akt, and JAK/STAT Signaling in Papillary Thyroid Cancer
This narrative review highlights the potential of naturally occurring compounds to target specific molecular pathways and overcome resistance in advanced and recurrent papillary thyroid cancer, offering new therapeutic possibilities beyond traditional treatments like surgery and lifelong hormone replacement.
research Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome
This review summarizes how foods with both medicinal and nutritional properties are being examined for their potential role in addressing post-acute COVID-19 syndrome, but it reports no new clinical results.
research Efficacy of exosomes in acute kidney injury treatment and the associated mechanism (Review)
This review discusses the potential therapeutic effects of exosomes from various cell sources in treating acute kidney injury and explores their mechanisms, but reports no new clinical results.
research Unveiling Post-COVID-19 syndrome: incidence, biomarkers, and clinical phenotypes in a Thai population
This study found that post-COVID-19 syndrome incidence varied significantly by gender and identified ALP levels as a potential biomarker for its detection, challenging current diagnostic criteria.
research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
This review highlights the importance of apoptosis in the hair cycle, particularly its role in hair follicle regression and loss, suggesting that understanding its mechanisms can aid in developing treatments to reduce hair loss and promote hair growth.
research Abstracts from the 55th European Society of Human Genetics (ESHG) Conference: e-Posters
This study observed that numerical chromosomal aberrations were more common in men with severe male factor infertility and azoospermia compared to those with other sperm quality issues, while chromosomal translocations were significantly associated with oligoasthenozoospermia, highlighting important genetic counseling considerations.
research Botryococcus terribilis Ethanol Extract Exerts Anti-inflammatory Effects on Murine RAW264 Cells
This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.
research Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells
This review summarizes recent findings about the multi-site differentiation of tissue regulatory T cells, emphasizing the pivotal role of epigenetic remodeling, but it reports no new clinical results.
research Mechanistic Insights into Plant-Derived Exosomes, Their Cross-Kingdom Effects, and Potential Biomedical Applications in Skin Wounds Repair
This review explores plant-derived exosomes as promising alternatives to synthetic wound-healing agents due to their ability to regulate signaling pathways involved in skin repair, while also addressing challenges in their clinical application.
research Clinical Evaluation of the MIRA Technique in Cellulite Treatment: A Retrospective Case–Control Study
This study found that the MIRA technique, using ultrasound-guided needle adjustments, improved cellulite treatment outcomes compared to standard methods in women with stage 3 cellulite, evidenced by greater reductions in adipose thickness and other skin irregularities, along with higher patient satisfaction.
research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
This review highlights how nanotechnology enhances CRISPR-Cas9's potential for cancer treatment by improving delivery and stability, addressing key challenges like immunogenicity and delivery inefficiencies, and discusses recent advancements in stimuli-responsive nanoplatforms for precise genome editing.
research Recent Progress and Morphological Distribution of Polydopamine-Based Biomaterials and Their Applications
This review discusses recent advances in polydopamine-based biomaterials and their growing potential in personalized medicine, but reports no new experimental results; the authors highlight both opportunities and challenges for future applications.
research Fenugreek as a Versatile Cosmetic Ingredient: Phytochemical Profile, Skin–Hair Benefits and Formulation Opportunities
This review highlights that Trigonella foenum-graecum L. (fenugreek) shows promise as a versatile plant-based ingredient in cosmetics due to its phytochemicals, which offer benefits for skin and hair care, although further research is necessary for robust validation.
research Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology
This paper reviews advancements in 3D human skin models using bioprinting, organoid, and organ-on-a-chip technologies, noting improvements in physiological realism through vascularization and multi-omics data, but also highlighting challenges such as cost and lack of standardization that hinder clinical adoption.
research Molecular crosstalk between lncRNA H19, miR-29a, and JAK2/STAT3 signaling in alopecia areata: a preliminary study
research Insulin Resistance, Metabolic Syndrome, and Inflammatory Skin Disease
This review identified significant associations between glucose dysregulation and various dermatological conditions like psoriasis and acne, suggesting that dietary interventions and probiotics may help manage related inflammation, highlighting the need for holistic treatment approaches for insulin resistance and metabolic syndrome.