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A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Finasteride may increase depression by reducing brain cell growth.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.

Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.

Finasteride use can cause depression-like behavior in male rats.

The article concludes that microvascular free flaps, especially the latissimus dorsi flap, are recommended for large scalp reconstructions, and hair transplantation offers high survival rates and excellent aesthetic results.

Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

Vogt-Koyanagi-Harada disease can develop during interferon therapy for chronic hepatitis C.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.