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Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The HR protein's role as a repressor is essential for controlling hair growth.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

Pannexin 3 is important for bone formation and the development of bone cells.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.