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The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

PEVs improve minoxidil skin penetration, increasing hair growth.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Liposomes could improve how skin care products work but are costly and not very stable.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Mannosylerythritol lipids are good for skin and hair care products.