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This study reports a novel LC/MS method that separates and analyzes all known ceramide subclasses in human stratum corneum, identifying a new subclass, CER [EOdS], with minimal sample preparation.

Radiation therapy with a higher dose for the brain improves survival in cerebellar medulloblastoma.

This study observed that androgenic alopecia patients taking finasteride had altered neuroactive steroid levels and persistent depression symptoms even after stopping the treatment.

This study found that mice deficient in ceramide synthase 4 showed altered sebum composition and progressive hair loss due to obstructed hair canals.

This study reports that men with androgenic alopecia experience altered neuroactive steroid levels associated with persistent depression symptoms even after stopping finasteride treatment.

This study found that inactivating CerS4 in mice led to hair follicle stem cell exhaustion and hair loss, indicating its role in regulating hair regeneration through ceramide composition and signaling pathways.

This study found that a ceramide derived from sphinganine can bind to African–American hair, reducing breakage when applied in a shampoo after relaxing treatments.

This study found that mice lacking alkaline ceramidase 1 with elevated skin ceramide levels showed disrupted skin homeostasis, including altered hair follicle structures, increased water loss, and a hypermetabolism phenotype.

This study found that a ceria nanozyme-integrated microneedles patch accelerated hair regeneration in an androgenetic alopecia mouse model more effectively than minoxidil, with reduced application frequency and minimal skin damage.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

This review discusses the use of ceramic-coated flat irons for hair straightening and reports no clinical results; the authors highlight potential hair damage risks from improper use.

In this study, 14 out of 15 women with scalp dysesthesia also had cervical spine disease, and gabapentin improved symptoms for some patients.

This study found that an injectable ceria-based nanocomposite hydrogel improved wound healing and epithelium regeneration, including hair follicle and adipocyte tissue formation, in full-thickness skin wound models.

This case report describes a 45-year-old Japanese woman with metastatic cervical cancer, including rare scalp metastases, who experienced severe scalp tenderness and patchy hair loss before her death.

This document provides a legal disclaimer and offers no research findings.

This study found that lncRNA H19 may regulate CTGF expression in KGN cells by acting as a "sponge" for miR-19b, potentially influencing polycystic ovary syndrome development.

This study found that loss of the ACER1 gene in mice led to increased ceramide levels and progressive hair loss, highlighting ACER1's role in maintaining hair follicle stem cell homeostasis.

This study observed that pregnant women with polycystic ovarian syndrome had a higher prevalence and incidence of cervical insufficiency compared to those without PCOS.

This study found weak to very weak correlations between estradiol, progesterone, and testosterone levels in the cerebrospinal fluid and serum of males without cerebral disorders.

Ceramide Synthase 4 is crucial for healthy skin barrier function.

This article reviews the role of sulfhydryl compounds, particularly cystine, in sulfur metabolism and the physiology of skin in both normal and pathological conditions, reporting no new findings.

This case report describes a young woman with ankylosing spondylitis who developed a severe paradoxical skin reaction after six months on certolizumab, requiring treatment with secukinumab and methotrexate.

This study found that root hairs in maize, wheat, and finger millet continued to grow beyond the typical root hair zone when grown with the Turface® fertigation system, highlighting potential for understanding root hair dynamics and crop improvement.

This study reports on the vulnerability of hair's structural lipids to physical and chemical damage and describes properties of hair treated with a synthesized ceramide derivative.

This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

Temporary hair loss can occur after brain AVM treatment but usually regrows in 8 weeks.

This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.

This study suggests that synthetic ceramides may promote hair growth by inducing proliferation of human dermal papilla cells through modulation of Wnt/β-catenin and BMP2/4 signaling pathways.