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      Wnt Signaling in Skin Development, Homeostasis, and Disease

      research Wnt Signaling in Skin Development, Homeostasis, and Disease

      260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
      5α-Reductase Activity in the Prostate

      research 5α-reductase activity in the prostate

      237 citations , December 2001 in “Urology”
      This review discusses the role of 5α-reductase in prostate development and BPH, and reports no new clinical results; ongoing trials are exploring dual isozyme inhibitors for improved treatment efficacy.
      Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives

      research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives

      233 citations , November 2002 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This review explores androgen metabolism in the skin, highlighting enzyme localization and potential implications for treating androgen-dependent skin conditions, but it reports no new clinical results.
      Is COVID-19 Gender-Sensitive?

      research Is COVID-19 Gender-sensitive?

      228 citations , January 2021 in “Journal of Neuroimmune Pharmacology”
      This review explores possible reasons for why male COVID-19 patients experience more severe symptoms and higher fatality rates than female patients but provides no new clinical results.
      Eph Receptors and Ephrins: Therapeutic Opportunities

      research Eph Receptors and Ephrins: Therapeutic Opportunities

      222 citations , October 2014 in “Annual Review of Pharmacology and Toxicology”
      This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
      Medical Treatments for Male and Female Pattern Hair Loss

      research Medical treatments for male and female pattern hair loss

      212 citations , September 2008 in “Journal of The American Academy of Dermatology”
      This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.
      Androgens and Hair Growth

      research Androgens and hair growth

      209 citations , September 2008 in “Dermatologic Therapy”
      This review discusses the role of androgens in hair follicle regulation and suggests that a better understanding could enhance treatments for conditions like hirsutism and alopecia, but does not present new findings.
      Cutaneous Complications of Chemotherapeutic Agents

      research Cutaneous complications of chemotherapeutic agents

      172 citations , November 1983 in “Journal of The American Academy of Dermatology”
      This article discusses the cutaneous side effects of various chemotherapeutic agents but reports no new clinical results; the authors emphasize the importance of dermatologists recognizing drug-induced skin reactions to better patient care.
      Anthracycline Analogs: The Past, Present, And Future

      research Anthracycline analogs The past, present, and future

      168 citations , December 1986 in “Cancer Chemotherapy and Pharmacology”
      Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
      The Human Tri-Peptide GHK and Tissue Remodeling

      research The human tri-peptide GHK and tissue remodeling

      165 citations , January 2008 in “Journal of biomaterials science. Polymer ed.”
      This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.
      Photobiomodulation or Low-Level Laser Therapy

      research Photobiomodulation or low‐level laser therapy

      160 citations , December 2016 in “Journal of biophotonics”
      This review discusses the evolution and potential of photobiomodulation therapy, highlighting its transition from skepticism to recognition in medical research; it reports no new experimental findings.
      The Pharmacology of Methotrexate

      research The pharmacology of methotrexate

      155 citations , August 1991 in “Journal of The American Academy of Dermatology”
      This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
      Caffeine’s Mechanisms of Action and Its Cosmetic Use

      research Caffeine’s Mechanisms of Action and Its Cosmetic Use

      153 citations , October 2012 in “Skin Pharmacology and Physiology”
      This review discusses the use of caffeine in cosmetics for its fat-reducing, antioxidant, and hair growth properties, but reports no new research findings.
      Ichthyosis

      research Ichthyosis

      147 citations , January 2003 in “American journal of clinical dermatology”
      This review discusses various forms of ichthyosis, including genetic and acquired types, detailing their characteristics, causes, and potential management strategies, but reports no new clinical results.
      Molecular Mechanisms of Viral Oncogenesis in Humans

      research Molecular mechanisms of viral oncogenesis in humans

      141 citations , August 2018 in “Nature Reviews Microbiology”
      This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.