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Sebaceous glands are often preserved and PPARy expression is constant in some cases of Central Centrifugal Cicatricial Alopecia.

The patient with both scarring and non-scarring hair loss showed complex immune reactions and improved with steroid treatment.

CCCA may be caused by both hair traction and an immune response.

Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.

Black women with CCCA are more likely to have uterine fibroids.

Topical metformin 10% cream may help treat central centrifugal cicatricial alopecia.

CCCA is a scarring hair disorder mainly affecting people of African descent, needing better awareness and treatment.

Patients with central centrifugal cicatricial alopecia often have higher rates of metabolic, autoimmune, and atopic conditions, as well as anxiety and depression.

Certain hairstyles, diabetes, scalp infections, and vitamin D deficiency may increase the risk of hair loss in Black women; more research is needed for better treatment.

The letter suggests that the study's comparison group might have affected the results and calls for larger, more detailed future research.

Wearing a high-quality wig improved a woman's mood and life quality, and the authors suggest insurance should cover the cost of wigs.

Most patients with Central Centrifugal Cicatricial Alopecia at the reviewed institution were middle-aged Black women, often with no symptoms, and commonly treated with topical medications.

More research is needed on CCCA in children, especially Black and Asian adolescents.

Some factors like thyroid disease, diabetes treatment, hair dryers, natural hairstyles, and scalp conditions can affect the treatment results for a hair loss condition called CCCA.

The authors maintain there is a significant link between vitamin D deficiency and central centrifugal cicatricial alopecia in Black patients, and call for more research on the topic.

Seborrheic dermatitis may contribute to the development of central centrifugal cicatricial alopecia.

COVID-19 may worsen hair loss in people with a certain type of scarring alopecia, but early treatment can help improve symptoms and hair regrowth.

Accurate diagnosis is crucial for effective treatment of hair loss.

CCCA is a common hair loss condition in African American women, often inherited and influenced by hairstyling, with unique scalp features detectable by special tools.

Certain immune markers may predict chemotherapy response in mesothelioma, and nivolumab is a tolerable and effective treatment for advanced non-small cell lung cancer.

Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.

CCCA and lichen planopilaris have similar histological features, making them hard to distinguish.

CCCA can affect both genders and all ages, and it has a genetic component.

A woman's severe hair loss was caused by scalp psoriasis, not the initially thought condition, and treatment improved her psoriasis but couldn't restore her lost hair.

Hair loss in African American women, caused by hair care, genetics, and environment, needs more research for better treatment.

Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.

848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.

A condition called Central Centrifugal Cicatricial Alopecia causes hair loss and scalp burning in middle-aged African women, and it's treated with various medications, hair transplants, and non-drug methods like wigs.