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HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

DHT may reduce inflammation caused by certain bacteria in skin cells.

A new earlobe repair method using cartilage grafts showed high satisfaction and no re-splitting.

Higher leptin levels link to hair loss.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Targeting colon cancer stem cells might lead to better treatment results.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.