March 2026 in “Editora Pasteur eBooks” This study reviews hair follicle physiology and common scalp diseases such as androgenetic alopecia, telogen effluvium, and alopecia areata, highlighting their pathophysiology and current treatment approaches, which may include topical, systemic, and adjunctive therapies.
April 2025 in “Revista JRG de Estudos Acadêmicos” This study examined the use of Instagram® to share scientific information about onychomycosis, a common nail fungal infection, and found it to be an effective tool for engaging a broad audience with educational posts about prevention and treatment over two months.
April 2024 in “International journal of women's health” This review explores adult female acne, focusing on its multifactorial causes, treatment options, and impact on quality of life, but reports no new clinical results.
September 2023 in “Tạp chí Y Dược học Cần Thơ” In this study on diabetic mice, researchers demonstrated that onion extract significantly lowered blood glucose levels at doses of 500mg/kg and 1,000mg/kg, showing comparable effectiveness to the diabetes medication metformin.
January 2023 in “Revista Paulista de Pediatria” This case study reported the first diagnosis of IFAP syndrome in Brazil with molecular investigation, identifying a rare MBTPS2 gene variant and expanding the known mutational spectrum associated with the condition.
December 2022 in “Revista Medicina Cutánea Ibero-Latino-Americana” This review summarizes current knowledge on the role of the JAK/STAT signaling pathway in alopecia areata and suggests moderate efficacy of systemic inhibitors, with low adverse events but high recurrence rates.
April 2021 in “Journal of Law Public Policies and Human Sciences” In this note, editors discuss the reproduction of medical content by Dr. Paul E. Marik, related to standardized coronavirus treatments, emphasizing that the materials appear effective and cautioning readers to consult their doctors for guidance.
This study found that among women with polycystic ovary syndrome, higher age, obesity, hirsutism, and having children were independently associated with increased metabolic risk.
January 2007 in “Revista del Centro Dermatológico Pascua” This review discusses female androgenic alopecia, highlighting its potential difference from male androgenic alopecia and notes increased incidence, but reports no new clinical findings.
1533 citations
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October 2008 in “Endocrine reviews” This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
555 citations
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July 2001 in “Genes & Development” This study found that Tcf3 and Lef1 differently regulate cell differentiation in multipotent skin stem cells, with Tcf3 promoting follicle-like features and Lef1, when modified, promoting sebocyte differentiation.
425 citations
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January 2021 in “SN Applied Sciences” This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
298 citations
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January 2014 in “BioMed Research International” This review discusses various methods for obtaining stem cell-derived conditioned media and its applications in disease treatment, finding generally positive results but highlighting the need for standardized production methods.
242 citations
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January 2000 This study identified a strong association between heavy metal contamination in drinking water and chronic diseases like renal failure and liver cirrhosis in Great Cairo Cities, Egypt.
238 citations
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February 2007 in “Journal of Neuroscience” This study found that neurosteroids can reorganize GABA A receptors in mice, mimicking ovarian cycle changes, with the process being mediated by neurosteroid levels rather than direct hormone receptor activation.
233 citations
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February 2018 in “Polymers” This review examines the roles and benefits of chitosan in cosmetics and oral hygiene, highlighting its potential in the cosmeceutical market, but it reports no new results.
228 citations
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September 2012 in “Trends in Neurosciences” This review examines the role of nerves in regeneration across various species and discusses their importance as components in the progenitor cell niche, reporting no new clinical results.
205 citations
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August 2007 in “Experimental Cell Research” This review discusses advances in understanding mammalian stem cell niches, particularly in bone marrow, tooth, and hair follicle, and highlights the potential for developing therapies targeting these niches for tissue repair.
199 citations
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April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
193 citations
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January 2015 in “International journal of trichology” This review examines hair cosmetics, including shampoos and conditioners, for their formulations and effects, but reports no new clinical findings; it emphasizes the importance of dermatologist knowledge in treating diverse hair conditions.
192 citations
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March 1998 in “British Journal of Dermatology” This study found that minoxidil significantly increases VEGF mRNA and protein expression in dermal papilla cells, suggesting a role in enhancing hair follicle vascularization in androgenetic alopecia.
165 citations
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January 2008 in “Journal of biomaterials science. Polymer ed.” This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.
146 citations
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May 2002 in “The American journal of pathology” This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.
144 citations
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March 2013 in “Circulation Research” This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
134 citations
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June 2012 in “International Journal of Oral and Maxillofacial Surgery” This article discusses current methods in facial feminization surgery for transsexual women and reports no new clinical results, focusing instead on various surgical techniques used to feminize facial features.
131 citations
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September 2010 in “The Laryngoscope” This study found that forehead feminization significantly contributes to recognizing female gender and reported that feminizing forehead cranioplasty is a safe procedure with a low complication rate.
120 citations
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November 2014 in “Biological Reviews” This article explores the dynamic and energy-efficient nature of telogen hair follicles, challenging the notion of dormancy, and highlights their potential in advancing treatments for hair growth disorders.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” This review provides an overview of recent tissue engineering and regenerative medicine developments in Asia, highlighting significant advances, representative research achievements, and discussing future directions, without presenting new research results.
118 citations
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December 2014 in “International Journal of Medical Sciences” This review discusses the potential of mesenchymal stem cells from the oral cavity for tissue regeneration in oral and maxillofacial surgery but reports no new clinical results.
116 citations
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September 2020 in “Nature Communications” This study reports previously unrecognized cellular complexity in growing mouse incisors, suggesting species-specific differences in cell dynamics between mouse and human teeth related to growth and differentiation.