April 2023 in “Journal of Investigative Dermatology” This study found that inhibiting PI3 kinase in epidermal stem cells reduces YBX1 phosphorylation, thereby decreasing cellular senescence and enhancing wound healing and regeneration in adult-derived skin models.
April 2023 in “Journal of Investigative Dermatology” Staphylococcus epidermidis affects hair growth and metabolism, suggesting it could help manage hair growth issues.
February 2023 in “Benha Journal of Applied Sciences” This article reviews R-Spondin-1's complex role in various skin conditions, emphasizing its diagnostic, prognostic, and potential therapeutic applications.
December 2022 in “KSBB Journal” This study suggests that autophagy is essential for regulating TLR3-mediated regenerative processes in human keratinocytes.
This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.
October 2022 in “Frontiers in Cell and Developmental Biology” Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
September 2022 in “Institutional Repositories DataBase (IRDB)” 3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.
June 2022 in “International Journal of Research -GRANTHAALAYAH” This article discusses the role of the hair follicle as a miniorgan involved in bioelectricity and energy transfer in living organisms, but it reports no new research findings.
June 2022 in “Ain Shams medical journal” This study found that incorporating platelet-rich plasma in hair transplant procedures for cicatricial alopecia improved patient satisfaction and hair growth outcomes compared to procedures without it.
January 2022 in “Pastic and aesthetic research” This article reviews the clinical use of platelet rich plasma for skin regeneration, highlighting the challenges of inconsistent outcomes due to varying preparation protocols, and calls for standardized models to better assess its effectiveness.
This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.
This study proposes that neutralizing antibodies and exosomes in convalescent plasma may interfere with early immune responses, potentially explaining limited success of this therapy in active COVID-19 infections.
This study identified a new isozyme, 5α-reductase-3, at the mRNA level in human prostate tissue, but its protein expression and cellular localization remain unclear.
April 2020 in “Rice Research Repository (Rice University)” This study suggests that MultiDomain Peptide hydrogels may support wound healing in diabetic mice by accelerating closure and promoting tissue regeneration, though they did not inhibit bacterial growth in infected wounds as expected.
March 2020 in “Journal of lasers in medical sciences” This study found that HERC6 and its neighboring genes play a significant role in the cellular response of human skin to CO2 laser therapy, highlighting key biological processes related to gene expression changes post-treatment.
This study suggests that the exercise-induced cytokine IL-15 can improve wound healing in aged skin, along with previously reported benefits on skin structure and mitochondrial function.
October 2019 in “Research Square (Research Square)” In this study, researchers identified and analyzed 8,753 circular RNAs in Aohan fine wool sheep, suggesting that certain circRNAs may play a crucial role in regulating wool follicle growth.
September 2019 in “Romanian Journal of Pediatrics” This article discusses the unique regenerative healing process in fetal skin that can occur without scarring, highlighting potential therapeutic targets to reduce fibrosis in postnatal wound healing.
August 2019 in “Journal of the American Academy of Dermatology” Ginseng and Albizia extracts help prevent hair thinning with age.
April 2019 in “Institutional Repositories DataBase (IRDB)” This study demonstrated that human iPSC-derived melanocytes, when transplanted into mice, can reconstitute pigmented hair follicles and integrate into normal tissue, suggesting their potential as a cellular therapy for depigmentation.
January 2019 in “Archives of dermatology and skin care” This preclinical study reported that the mix of biomimetic peptides, MGF, promoted hair growth and increased cell proliferation in cultured human hair follicles from AGA subjects.
January 2019 in “Advances in stem cells and their niches” This review outlines the various fibroblast subsets in the skin dermis, their origins, and their influence on epidermal stem cell behavior, highlighting the role of the local dermal niche in stem cell plasticity.
January 2019 in “Institutional Repositories DataBase (IRDB)” This study achieved regeneration of hair follicle-like structures and erector muscle of hair in vitro by simulating cellular organization and applying mechanical stimuli.
January 2019 in “Institutional Repositories DataBase (IRDB)” This study developed in vitro methods to regenerate hair follicles and erector muscles by mimicking their native structures and mechanical conditions, reconstructing hair follicle-like structures and forming muscle-like tissues.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that age-related changes in scalp dermal fibroblasts, including increased MMP-1 and reduced ECM components, may significantly affect the hair follicle environment and contribute to hair aging.
April 2018 in “Journal of Investigative Dermatology” This study found that inhibiting NF-κB Essential Modulator (NEMO) in senescent murine dermal fibroblasts successfully reduced key factors associated with the senescence associated secretory phenotype (SASP), highlighting its potential as a therapeutic target for aging-related diseases.
February 2018 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study concluded that macrophage iron retention due to Ferroportin inactivation hinders skin wound healing but does not affect liver damage or fibrogenesis in a mouse model.
January 2018 in “Open access journal of pharmaceutical research” In this study, researchers found that Biofield Energy Healing Treatment significantly increased the proliferation of human hair follicle dermal papilla cells in vitro, suggesting potential hair growth benefits.
January 2018 in “Clinical dermatology open access journal” This review discusses the various applications of chitosan-based materials in dermatology and highlights their potential as promising new materials but does not present new experimental results.
This study explores the expression and function of 11β-HSD1 in human hair follicles and its potential regulation of glucocorticoid effects on dermal papilla cells, but reports no definitive findings on 11β-HSD1's role.