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5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Certain genes control the color of human hair by affecting pigment production.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Finasteride helps reduce heart issues and improves heart function.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Chemokine signaling is important for hair development.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

New genes found linked to balding, may help develop future treatments.

LED light therapy may help hair growth by activating certain cell pathways.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.