21 citations
,
January 2023 in “The International Journal of Developmental Biology” This review examines the Wnt signaling pathway's role in regeneration across key model species, but it reports no new findings and highlights the need for more research to understand the underlying molecular mechanisms.
12 citations
,
January 2007 in “Acta dermato-venereologica” This review discusses the classification and regulation challenges of anti-ageing cosmetics in Europe and reports no new findings; it calls for increased transparency to help consumers make informed choices.
2 citations
,
March 2019 in “Lasers in surgery and medicine” This study found that human hair follicles demonstrated a dose-dependent response to light in an ex vivo photoepilation model, which could predict the clinical efficacy and permanency of light-based hair removal devices.
1 citations
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January 2026 in “Frontiers in Bioengineering and Biotechnology” This review discusses various nanocarriers for gene and genome editing therapies, highlighting that ionizable lipid nanoparticles show advanced delivery performance, while emerging polymer-based and exosome-inspired carriers are rapidly advancing for targeted applications.
January 2024 in “Wiadomości Lekarskie” In this study, researchers developed a novel computational framework using deep reinforcement learning to identify strategies for cellular reprogramming in gene regulatory networks, showing its effectiveness in a model of immune response against infection.
November 2023 in “Linköping University medical dissertations” This research presents a comprehensive workflow for producing EMA-compliant autologous keratinocyte-based therapies for wound healing and explores miRNA-mediated regulations in human keratinocytes and adipose-derived mesenchymal stem cells.
17 citations
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August 2014 in “American Journal of Physiology-gastrointestinal and Liver Physiology” This study found that finasteride significantly improved motor, EEG, and cellular changes in a rat model of thioacetamide-induced hepatic encephalopathy and prevented the development of hepatic coma.
September 2025 in “Experimental & Molecular Medicine” This study observed that the small molecules KY19382 and KY19334 inhibited cancerous traits in human cutaneous squamous cell carcinoma cells by suppressing the Wnt/β-catenin pathway, indicating their potential as treatments for cancers involving CDK1 overexpression and diseases related to CXXC5 accumulation.
June 2025 in “International Journal of Nephrology and Renovascular Disease” This study suggests that PLA2R1 overexpression in PMN affects the podocyte cycle and may involve an additional immune response, which could provide new directions for PMN treatment development.
June 2020 in “Journal of Investigative Dermatology” This study reported that a treatment serum containing ingredient blends with panthenol, licorice extract, and red clover extract significantly improved hair volume, scalp coverage, and reduced hair breakage over 6 months in individuals with thinning or damaged hair.
August 2019 in “Placenta” This article reviews the use of spironolactone in dermatology for conditions like female acne, suggesting it may reduce antibiotic and isotretinoin use, and stresses its long-term safety.
2 citations
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October 2022 in “International journal of Ayurvedic medicine” This review examines the traditional uses and biological activities of Glycyrrhiza glabra in Ayurveda, but reports no new clinical results; the authors identify a gap in evidence supporting its medicinal potential.
April 2026 in “BMC Biotechnology” This study found that curcumin spanlastics demonstrated greater antimicrobial, antioxidant, and anticancer activities in the MCF-7 breast cancer cell line compared to curcumin alone or curcumin nanocrystals, also affecting several cancer-related protein markers and showing enhanced solubility and activity.
September 2020 in “Medicina Moderna - Modern Medicine” This study found that a simple two-step method for preparing platelet-rich plasma produced satisfactory quality at a lower cost compared to many commercial systems, enabling smaller medical institutions to utilize PRP therapy.
8 citations
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October 1989 in “Journal of the American Academy of Dermatology” In this study, researchers observed that purpuric, telangiectatic, lichenoid balanitis was the most common histologic pattern in cases of chronic pseudoerythroplastic balanitis, suggesting a possible link to lichen aureus.
74 citations
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August 2023 in “Frontiers in Immunology” In this review, the authors explored the diverse roles of fibroblasts in wound healing, suggesting that understanding their complexity could lead to better insights into wound pathologies and the development of new treatments.
April 2017 in “Journal of Investigative Dermatology” This study identified the dermal sheath as a key component of the hair follicle niche, essential for outer root sheath regression during the hair cycle, highlighting its importance in hair follicle support and regulation.
11 citations
,
January 2018 in “Royal Society Open Science” This study investigated the formation of Type III brush hair in Chinese Haimen goats and identified genetic factors that may involve heat stress in the process.
252 citations
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April 2009 in “Seminars in Cell & Developmental Biology” This review discusses the complex role of the immune system in tissue repair and regeneration, highlighting its positive and negative influences but reports no new clinical findings.
159 citations
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November 2007 in “American Journal of Pathology” In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.
16 citations
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May 1998 in “International Journal of Dermatology” This study found that elevated serum cortisol levels and other immunological changes are significantly involved in the active phases of psoriasis eruptions.
5 citations
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October 2017 in “Cellular Reprogramming” This research found that inhibiting HSP90 in a murine model increased cellular plasticity, suggesting a potential role for HSP90 in cancer progression through enhanced adaptability to stress.
4 citations
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February 2022 in “International Journal of Molecular Sciences” This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.
September 2025 in “International Journal of Science and Research (IJSR)” This theoretical review analyzes how stress affects hair loss through hormonal and neural pathways, indicating that knowledgeable hairdressers could help in early detection and guide clients toward medical interventions, highlighting a potential collaboration between aesthetic care and medical treatment for stress-induced alopecia.
March 2025 in “Aging Cell” In this study on mice, elevated IGF-1 levels in the skin were linked to premature aging of hair follicles, but interventions like reducing IGF-1 or using senolytic treatments helped restore stem cell health and counteract aging effects.
January 2022 in “Clinical dermatology open access journal” This review summarizes research on cannabinoids like CBD and THCV, reporting that they improve hair growth in patients with androgenetic alopecia when applied topically, with CBD showing a dose-dependent effect.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that age-related changes in scalp dermal fibroblasts, including increased MMP-1 and reduced ECM components, may significantly affect the hair follicle environment and contribute to hair aging.
29 citations
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May 2020 in “npj Regenerative Medicine” This review discusses the role of the immune niche in hair follicle regeneration and its impact on different forms of alopecia, highlighting research gaps and potential therapeutic strategies.
192 citations
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October 1998 in “Experimental Dermatology” This article examines the terminal to vellus transition in androgenetic alopecia through cellular and developmental mechanisms, discussing challenges and knowledge gaps without presenting new clinical findings.
74 citations
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May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” This review identifies shared interferon gamma-driven immune pathways in vitiligo and alopecia areata, revealing potential targets for new treatments, but reports no clinical results.