research Modeling the Onset of Senescence-Associated Secretory Phenotype Predicts Therapeutic Targets
The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
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research External Light Activates Hair Follicle Stem Cells Through Eyes Via the ipRGC-SCN-Sympathetic Neural Circuit
Light can activate hair growth through a pathway from the eyes to hair follicles.
research Hair Regeneration by Small Molecules That Activate Autophagy
Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
research Single Molecule FISH for Hedgehog Signaling in Mouse Skin
Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Stromal Re-Organization in Hair Follicle Development and Cancer Suppression
Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
research Hairy Math: Addition of Wnt-3a to Multiply Bulge Cells
Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
research Skin Structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research In This Issue
Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
research The Variable Cell
Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
research Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research Regeneration of Fat Cells from Myofibroblasts During Wound Healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.
research Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation
Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
research Nerve Dependence in Tissue, Organ, and Appendage Regeneration
Nerves are crucial for the regeneration of various body parts in many animals.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation
Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
research Stem Cell Niches in Mammals
Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
research Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration
Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
research Roles of Jumonji and Jumonji Family Genes in Chromatin Regulation and Development
Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology
Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
research Epidermal Stem Cell Diversity and Quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Molecular Biology of Hair Morphogenesis: Development and Cycling
Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
research Do Men's Faces Really Signal Heritable Immunocompetence?
Masculine facial features may not reliably indicate heritable health, and more research is needed.
research Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
research Biology of the Wool Follicle: An Excursion into a Unique Tissue Interaction System Waiting to Be Rediscovered
The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
research Principles of Hair Cycle Control
Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Fullerene Nanoparticles in Dermatological and Cosmetic Applications
Fullerenes show potential in skin care but need more safety research.
research Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells
Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.