1 citations,
January 2018 in “Recent clinical techniques, results, and research in wounds” Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
38 citations,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
27 citations,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
25 citations,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
19 citations,
November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.
9 citations,
May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
August 2019 in “Journal of Investigative Dermatology” The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
211 citations,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
91 citations,
December 2010 in “Stem Cells” Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
68 citations,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
67 citations,
December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
65 citations,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
42 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
40 citations,
July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
30 citations,
December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
25 citations,
September 2014 in “Biological Research” Arctiin helps protect hair cells from damage and death caused by oxidative stress.
19 citations,
January 2015 in “Scientific Reports” GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
15 citations,
January 1995 in “Archives of dermatological research” OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.
12 citations,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
11 citations,
May 2018 in “Philosophical Transactions of the Royal Society B” New materials help control stem cell growth and specialization for medical applications.
10 citations,
September 1997 in “Molecular carcinogenesis” Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
9 citations,
July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
6 citations,
July 2021 in “Microbial biotechnology” The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.
5 citations,
October 1988 in “Clinics in Dermatology” Minoxidil promotes hair growth but exact mechanism is unknown.
4 citations,
January 2022 in “Journal of clinical and translational research” Chitosan-based dressings reduce inflammation and speed up skin wound healing.
4 citations,
March 2019 in “Experimental Biology and Medicine” Exposure to 50 Hz electromagnetic fields may help mice grow hair faster.
4 citations,
November 2016 in “Dermatologic Therapy” Topical tretinoin may increase beard hair density.
3 citations,
August 2019 in “Journal of The American Academy of Dermatology” PRP with microneedling is generally safe but can cause minor side effects like scalp itching, temporary hair shedding, and swollen lymph nodes.