89 citations,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
64 citations,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
46 citations,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
35 citations,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
32 citations,
May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
23 citations,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
20 citations,
November 2019 in “Current Opinion in Systems Biology” The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
1 citations,
December 2022 in “Biomolecules & therapeutics” Minoxidil may help reduce aging effects in brain cells.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
January 2018 in “Open access journal of pharmaceutical research” Biofield Energy Healing may increase hair growth by enhancing cell proliferation.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
18 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
3 citations,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
2 citations,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Adipocytes can change into fibroblast-like cells to help with wound healing.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
1 citations,
January 2011 in “Springer eBooks” Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
116 citations,
September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
31 citations,
November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
2 citations,
November 2022 in “BioMed Research International” Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
30 citations,
April 2017 in “Experimental Dermatology” Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.
April 2016 in “Journal of Investigative Dermatology” The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
610 citations,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
438 citations,
October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
359 citations,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
156 citations,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
25 citations,
May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
21 citations,
July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.