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This study found that LED light irradiation induced proliferation and migration of human outer root sheath cells, potentially through the stimulation of the Wnt/β-catenin and ERK signaling pathways.

This review highlights challenges in developing drugs targeting the Wnt/β-Catenin signaling pathway for cancer due to its complexity and essential roles in normal tissue. It explores targeted protein degradation technology as a promising strategy to overcome these challenges, suggesting potential new avenues for drug development.

This study analyzed gene expression in Pashmina goats and identified key biological processes and molecular functions involved in long-fibre production, suggesting potential pathways for enhancing this trait in other goat breeds.

This study suggests that black ginseng concentrate protects human follicle dermal papilla cells against oxidative stress, potentially offering a natural approach to prevent cellular dysfunction linked to hair loss.

This study found that in Arabidopsis thaliana, the interaction between extracellular leucine-rich repeat extensins and the receptor-like kinase FERONIA helps control vacuolar expansion, crucial for cellular elongation.

This study found that ginsenoside Rf from Panax ginseng may serve as an effective anti-pigmentation agent by inhibiting the CREB/MITF pathway, reducing melanogenesis in melanocytes and UV-irradiated human skin.

In this study, Wang et al. (2022) found that in patients with cutaneous lupus erythematosus, chronic lesions contained more senescent progenitor cells, marked by p16 and p21, than subacute lesions, suggesting a link between disease chronicity and cellular senescence.

In this review, the authors explored the diverse roles of fibroblasts in wound healing, suggesting that understanding their complexity could lead to better insights into wound pathologies and the development of new treatments.

This review discusses the role of the Wnt/β-catenin pathway in skin wound repair and explores how photobiomodulation may affect chronic wound healing, but it reports no new clinical results.

In this study, exosomes derived from Iris germanica L. rhizomes (Iris-exosomes) were reported to alleviate oxidative stress and improve mitochondrial function in human follicle dermal papilla cells by activating the Wnt/β-catenin signaling pathway, suggesting potential benefits for hair loss treatment.

This study suggests that selenium deficiency contributes to aging signs and health deterioration in a mouse model, supporting selenium's role in genome maintenance and protection against oxidative stress.

This study found that c-Jun is essential for vitamin D receptor expression, and the vitamin D receptor inhibits c-Jun-dependent cell death through non-classical mechanisms independent of vitamin D3.

In this study, blue light-irradiated nanovesicles derived from human adipose-derived stem cells enhanced dermal fibroblast proliferation and extracellular matrix synthesis, improving skin maintenance and hair follicle regeneration, suggesting a novel therapeutic strategy for skin and hair disorders.

Water extract of cacumen platycladi helps hair growth by affecting specific cell pathways.

This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.

This study suggests that β-Catenin and extracellular matrix components interact in a regulatory loop to influence fibroblast behavior and wound repair properties in dermal tissue.

This review discusses the potential of small extracellular vesicles (sEVs) as next-generation therapeutics, noting their ability to overcome biological barriers and modulate cellular environments for various diseases.

In this study, researchers discovered that fat grafting helps reduce dermal fibrosis in radiation-injured mouse skin by decreasing specific fibroblast subpopulations associated with Fra/c-Jun signaling.

Caffeine can damage hearing cells and affect hearing recovery after ear trauma.

This review examined the pathological effects of mechanical pressure on human skin at the cellular level, highlighting how various skin cell types respond to pressure, potentially leading to pathological changes such as inflammation, ischemia, and impaired differentiation.

This study highlights the potential of extracellular vesicles derived from HuMSCs and lncRNA VIM-AS1 to enhance wound healing in diabetic conditions, suggesting innovative strategies for tissue repair.

This study found that cepharanthine significantly inhibits EqHV-8 infection in vitro and improves lung tissue pathology in infected mice by reducing oxidative stress through specific signaling pathways, suggesting its potential as a treatment for equid herpesvirus type 8.

This study found that metformin, an AMPK activator, promoted hair growth in vitro by enhancing the AMPK/β-catenin signaling pathway in dermal papilla and outer root sheath cells.

This study found that EGFR signaling modulates GLI target gene expression, potentially influencing outer root sheath cell specification and hair growth, and may have implications for cancer.

This review discusses the therapeutic effects of soft laser therapy on humans and animals, highlighting increased ATP and reactive oxygen species production in cells with high mitochondrial activity.

Different types of stem cells and their environments are key to skin repair and maintenance.

This review examines PAK4 signaling pathways in prostate cancer, Parkinson's disease, and melanogenesis, focusing on the potential role of the PAK4-CREB axis, without reporting new clinical results.

In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.

This review discusses the regulation of the MiT-TFE family transcription factors, particularly TFEB, through phosphorylation-mediated subcellular localization and reports no new clinical results.

In this study, researchers found that hair follicle orientation in Fz6 −/− mice is disrupted and that hair may reorient itself over time through a self-organized process.