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Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Advanced human skin models improve drug development and could replace animal testing.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

RANK-RANKL signaling is essential for hair growth and skin health.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.