19 citations
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January 2018 in “Scientific Reports” This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.
February 2008 in “Experimental dermatology” This article reviews potential pathomechanisms of vitiligo, emphasizing membrane alterations involving cholesterol and cardiolipin, but reports no new clinical findings.
25 citations
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October 1975 in “Journal of Cutaneous Pathology” This study found that in alopecia areata, hair bulbs are blocked in an early growth stage due to impaired metabolic function in the surrounding connective tissue, hindering hair growth.
January 1987 in “Data Archiving and Networked Services (DANS)” This article discusses the metabolism of benzo(a)pyrene in chemical carcinogenesis and reports no new experimental findings.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, periodic exposure to red light in aged mice led to increased histone acetylation and activated mitochondrial fatty acid oxidation, which collectively mitigated cellular aging by modulating metabolism, inflammation, and gene expression.
This study found that periodic red light exposure in aged mice increased histone acetylation and activated metabolic processes in keratinocytes, mitigating cellular aging through enhanced fatty acid oxidation and altered gene expression related to lipid metabolism.
This study found that periodic red light exposure increased histone acetylation and activated metabolic processes in aged mice, leading to enhanced fatty acid oxidation and the mitigation of cellular aging by influencing gene expression and metabolic regulation.
1 citations
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January 2024 in “Food Science and Technology Research” In this study, researchers evaluated the hair growth-promoting effects of strawberry water-extract on human follicle dermal papilla cells and found it enhanced cell metabolism, though it did not significantly alter hair growth-related gene expression.
1 citations
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September 2018 in “International journal of research - granthaalayah” This paper introduces a new understanding that the human hair follicle medulla lacks metabolic activity for H2O2 breakdown, indicating that H2O2 decomposition occurs primarily in the cortical areas.
12 citations
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June 2022 in “International Journal of Molecular Sciences” In this study, copper was found to promote the proliferation of dermal papilla cells in Rex rabbits by maintaining the function of the cellular mitochondrial electron transport chain.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” This research abstract provides no results, focusing on the equal contributions of the authors in the field of molecular, cellular, and developmental biology from Yale University.
10 citations
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June 2018 in “Journal of visualized experiments” This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.
This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.
3 citations
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July 2025 in “Stem Cell Research & Therapy” This study highlights the potential of extracellular vesicles derived from HuMSCs and lncRNA VIM-AS1 to enhance wound healing in diabetic conditions, suggesting innovative strategies for tissue repair.
305 citations
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March 2008 in “AJP Endocrinology and Metabolism” This article reviews the regulation and roles of spermidine/spermine-N(1)-acetyltransferase (SSAT) in polyamine metabolism and its potential as a target in cancer and other diseases, without reporting new experimental results.
7 citations
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October 2024 in “Cells” The researchers reported that autophagy, a lysosome-dependent degradation mechanism, plays a significant role in the cellular remodeling of keratinocyte differentiation in the skin, affecting the properties of the differentiation products by altering cellular components during this process.
2 citations
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December 2025 in “Annals of Medicine” This review discusses the complex correlation between cellular senescence and PCOS, emphasizing senescence markers, mechanisms, and potential anti-senescence therapies, but reports no new clinical results.
This study found significant differences in cashmere fiber diameters between two groups of cashmere goats and identified 211 genes and 50 metabolites related to hair follicle growth and cellular functions, suggesting potential pathways to improve cashmere quality.
September 2024 in “Wound Repair and Regeneration” This study explored the molecular factors behind delayed wound healing in obesity, highlighting that systemic changes like inflammation and collagen deposition alterations contribute to sustained skin inflammation and reduced mechanical resistance.
April 2018 in “Journal of Investigative Dermatology” This study suggests that human hair follicles may operate their own Cori cycle, synthesizing glycogen from lactate under conditions of lactic acidosis.
6 citations
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December 2023 in “Journal of Clinical Medicine” This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.
4 citations
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June 2022 in “Journal of food bioactives” This review discusses long-term health impacts and physiological disruptions experienced by COVID-19 survivors, highlighting the potential of nutritional interventions to manage post-acute sequelae and metabolic complications.
January 2026 in “Burns & Trauma” Low oxygen and metabolic changes help organoids grow and repair tissues.
83 citations
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May 2022 in “Journal of Advanced Research” This study suggests that enhancing glycolysis in MSCs may improve their immune functions and therapeutic potential, although more evidence is needed to understand the direct metabolic mechanisms involved.
1 citations
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April 2016 in “Journal of Investigative Dermatology” In this study, PGD2 treatment in keratinocytes increased testosterone production via reactive oxygen species, suggesting a potential role for the NRF2 pathway in androgenic alopecia treatment strategies.
November 2025 in “Phytomedicine” This study identified rhamnose as a compound that promotes hair growth by enhancing glycolysis and stimulating hair follicle regeneration, highlighting its potential use in alopecia treatment through animal and human organ culture models.
September 2017 in “Journal of Investigative Dermatology” This study found that stabilizing HIF1A in hair follicle cells promoted a shift to glycolysis, potentially reducing oxidative stress and promoting hair growth, particularly in balding dermal papilla cells.
April 2026 in “Molecules” This study suggests that extracellular vesicles derived from Saccharomyces cerevisiae may enhance hair follicle-related cellular processes, highlighting their potential for biomedical and cosmetic applications.
July 2022 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
October 2024 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This study suggests that follicular unit viability during hair transplantation is best preserved at lower storage temperatures, specifically around 4 °C, and provides insights into optimal cooling practices to enhance transplant success.