March 2024 in “Antioxidants” This study examines the effects of excessive or prolonged exposure to blue light on retinal function and highlights its potential health implications, noting that both photoreceptor and intrinsically photosensitive retinal ganglion cells (ipRGCs) are particularly sensitive to blue wavelengths.
57 citations
,
January 2022 in “Biomedicines” This review outlines curcumin's dual role as a radiosensitizer in cancer cells and a radioprotector in healthy cells, drawing on recent experimental and clinical findings.
February 2024 in “Molecules/Molecules online/Molecules annual” In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.
January 2011 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study found that a combination of spermidin, rutine, and zeaxantine effectively reduced staurosporin-induced apoptosis in cultured hair follicle dermal papilla cells, potentially preventing the regression phase in the hair follicle cycle.
29 citations
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October 2019 in “Journal of dermatological science” This review explores how cell and mouse models have contributed to understanding the mechanisms of human aging, particularly focusing on Hutchinson-Gilford Progeria Syndrome, and reports no new clinical results.
295 citations
,
September 2006 in “Cell Cycle” This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.
255 citations
,
September 2016 in “Frontiers in plant science” This article reviews recent insights into the regulatory role of reactive oxygen species in plant development, highlighting that their mechanisms and signaling pathways remain partially understood.
11 citations
,
March 2017 in “Sovremennye tehnologii v medicine” This review discusses various human skin equivalents, including those involving stem cells, and compares their structure and application, without presenting new clinical findings.
January 2017 in “Durham e-Theses (Durham University)” This study developed new label-free imaging methods to analyze human hair, identifying distinct chemical environments within cuticle layers and changes in hair structure caused by depilatories, while showing that the treatments tested did not significantly affect skin cell differentiation or proliferation.
59 citations
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November 2015 in “International Journal of Cosmetic Science” This review considers oxidative stress effects on hair aging and emphasizes the need for dermatologists to recognize and treat factors affecting scalp and hair health, but it provides no new clinical findings.
19 citations
,
July 2018 in “Mechanisms of Ageing and Development” This review examines how caloric restriction could promote autophagy to rejuvenate aging stem cells, though the precise molecular mechanisms remain unclear.
1 citations
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July 2023 in “Frontiers in Immunology” This review highlights the role of chronic stress, oxidative stress, and immune processes in the development of Hashimoto’s thyroiditis and polycystic ovary syndrome, emphasizing the potential of antioxidants in their treatment based on the existing literature.
1 citations
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June 2011 in “InTech eBooks” This review discusses the role of melanocytes in skin pigmentation and UV protection, explaining their interactions with keratinocytes and highlighting their involvement in processes like melanin transfer and melanoma development, but reports no new results.
April 2026 in “Frontiers in Immunology” This study concluded that the CXCL12–CXCR4 signaling pathway significantly contributes to hair loss in androgenetic alopecia and alopecia areata by promoting inflammation and fibrosis, whereas inhibiting this pathway can restore hair growth and follicle health.
This study found that an injectable hydrogel, SF-g-SDA, outperformed commercial Tegaderm™ in healing wounds, promoting collagen deposition, and enhancing neovascularization in animal models.
April 2020 in “The Aesthetics” This article discusses the applications and proposed benefits of LED low level light therapy for various conditions like acne, wound healing, and pain relief, but provides no new clinical results.
January 2012 in “Human health handbooks” This review discusses the application of low-level light therapy for hair loss treatment, particularly androgenetic alopecia, and reports no new clinical results; the authors suggest consideration of light source characteristics and potential pros and cons.
171 citations
,
October 1990 in “Alcoholism/Alcoholism, clinical and experimental research” The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
9 citations
,
February 2022 in “Biomolecules” This review concludes that while many epidemiological studies suggest high alcohol intake is associated with an increased risk of prostate cancer, the evidence may be affected by confounding factors such as diet and lifestyle.
20 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.
36 citations
,
September 2009 in “Journal of Cellular and Molecular Medicine” This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.
28 citations
,
November 2018 in “Journal of Cellular and Molecular Medicine” This review discusses the role of the CXXC5 protein as a transcription factor and signaling coordinator, noting its involvement in embryonic development, tissue homeostasis, and diseases such as tumorigenesis, but reports no new experimental findings.
16 citations
,
February 2019 in “Journal of Cellular and Molecular Medicine” This study established a rat model of radiation-induced dermatitis using 90 Gy irradiation, which may aid in exploring new treatments and understanding the pathology, particularly highlighting autophagy regulation as a potential therapeutic target.
This study found that DNA damage in obese women was linked to serum 25-hydroxyvitamin D and hair chromium levels, with higher serum vitamin D associated with less damage and higher chromium with more damage.
April 2024 in “Cellular signalling” This study on mice found that activating TRPML channels with MLSA1 promoted hair regeneration, accelerated hair cycle transition, and influenced human dermal papilla cells to secrete hair growth promoting factors while reducing hair growth inhibitors and oxidative damage.
33 citations
,
January 2018 in “The International Journal of Developmental Biology” This review discusses the dual role of cellular senescence in ageing and tissue repair and suggests potential therapeutic applications, with no new experimental results reported.
19 citations
,
April 2020 in “Oxidative Medicine and Cellular Longevity” This study provides evidence that Fernblock® upregulates antioxidant pathways in cultured keratinocytes, potentially protecting against damage from fine pollutant particles.
52 citations
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January 2005 in “International journal of experimental pathology” This study suggests that melatonin may have a radioprotective role against X-ray-induced skin damage in rats, as evidenced by milder injury markers in pretreated animals.
January 2026 in “Frontiers in Bioscience-Landmark” This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.
53 citations
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October 2014 in “Free radical biology & medicine” This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.