research Advanced Age Impairs Self-Renewal and Biases Fate Choice of Hair Follicle Dermal Stem Cells
Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
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research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
research Nrf2 Activation Enhances the Healing of Cutaneous Wounds Through the Activation of Hair Follicle Stem Cells
Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.
research Efficacy of Topical Tofacitinib in Promoting Hair Growth in Non-Scarring Alopecia
Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.
research Redox-Directed Interventions Targeting Skin Photodamage
Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
research Sirtuins Pathways and Redox Homeostasis: A Pilot Study on Young and Old Monozygotic Twins
The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.
research Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice
Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.
research Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway
Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.
research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
research Pregestational Overweight/Obesity Are Associated With C-Section and LGA Newborns in Women Attended in the Public Health System in Chile Between 2015-2017
Being overweight or obese before pregnancy increases the risk of having a C-section and a larger-than-normal baby in Chile's public health system.
research Claudin-1 and Claudin-3 Maintain Proper Hair Follicle Structure and Regulate Telogen Effluvium
Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.
research Nicotinic Acid Suppresses Sebaceous Lipid Synthesis of Human Sebocytes via Activating Hydroxycarboxylic Acid Receptor 2 (HCA2)
Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
research Orchestrated Cytotoxic and Skin Migratory Ability Lacking Self-Tolerance: Circulating γδT-Cells May Promote Alopecia Areata
The role of γδT-cells in causing alopecia areata remains unclear.
research Both Lesional and Non-Lesional Skin from Acne Patients Shows Robust IL-17-Skewing and Upregulation of Antimicrobial Peptides
Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research Ginsenoside Rb1 Promotes the Growth of Mink Hair Follicle via PI3K/AKT/GSK-3β Signaling Pathway
Ginsenoside Rb1 from Panax ginseng helps mink hair grow by activating certain cell signals.
research Resveratrol Derivatives: A Patent Review (2009–2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Arctiin Blocks Hydrogen Peroxide-Induced Senescence and Cell Death Through MicroRNA Expression Changes in Human Dermal Papilla Cells
Arctiin helps protect hair cells from damage and death caused by oxidative stress.
research Diabetex: A Novel Approach for Diabetic Wound Healing
Diabetex improves diabetic wound healing better than metformin.
research Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme
Certain Dibenzo derivatives may help treat prostate cancer.
research Expanding Research and Development of Novel Agents for the Treatment and Prevention of Chemotherapy-Induced Alopecia
No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.
research Wound Healing and Curative Properties of Alligator Pepper (Aframomum Melegueta) Seed Extract in Albino Rats (Rattus Norvegicus)
Alligator pepper seed extract improved wound healing in rats.
research The Effect of Platelet Rich Plasma (PRP) in Hair Regrowth: A Randomized Placebo-Controlled Trial
research Skin Disorders in Diabetes Mellitus
Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.
research Clinical Trial and In Vitro Study Investigating Topical Application of Zataria Multiflora Boiss. and Matricaria Chamomilla Extracts for Androgenetic Alopecia
Extracts improve hair growth in alopecia.
research Zinc Therapy in Dermatology: A Review
Zinc is effective for treating various skin conditions, including warts and acne.
research Hormesis And Medicine: Biphasic Dose-Response Relationship
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Oxidative Stress and Autoimmune Skin Disease
Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.