research Dickkopf-1 Expression in Androgenetic Alopecia and Alopecia Areata in Male Patients
DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.
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research Is There a Role for Dermatologists in Eating Disorders?
Dermatologists can help detect and manage eating disorders by recognizing skin changes.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research A Case of Recalcitrant Pediatric Vogt-Koyanagi-Harada Disease Successfully Controlled with Adalimumab
Adalimumab helped control a child's severe eye disease when other treatments failed.
research The Shifting Landscape of Disease-Modifying Therapies for Relapsing Multiple Sclerosis
New treatments for relapsing multiple sclerosis are more effective and convenient but have higher risks of serious side effects.
research iNOS Inhibits Hair Regeneration in Obese Diabetic (ob/ob) Mice
iNOS contributes to hair loss in obese diabetic mice and blocking it may encourage hair growth.
research Hair Growth in a Patient with Alopecia Areata on Tocilizumab
A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.
research Androgenetic Alopecia: Causes, Treatments, and Genetic Factors
Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.
research Effect of Polarized Light Therapy on Hair Regrowth in Alopecia Areata
Polarized light therapy helps hair regrowth in alopecia areata patients.
research Hair Biology and Nutritional Influences
Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.
research Assessment of Retinol-Binding Protein 4 in Patients with Alopecia Areata and Androgenetic Alopecia
Higher RBP4 levels found in people with two types of hair loss.
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration
Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
research Cutting Edge: Memory Regulatory T Cells Require IL-7 and Not IL-2 for Their Maintenance in Peripheral Tissues
Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Zinc Deficiency and Its Management in the Pediatric Population: A Literature Review and Proposed Etiologic Classification
Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
research Treatment of Generalized Lichen Planus With Alefacept
Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.
research Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications
Adrenal disorders can cause lasting brain and behavior issues in children.
research Hair Loss in Elderly Women: A Dermatological Concern
Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.
research Alopecia Areata Presenting in Two Kidney-Pancreas Transplant Recipients Taking Cyclosporine
Two transplant patients on cyclosporine unexpectedly developed hair loss.
research What's New in Cicatricial Alopecia?
New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
research Male Fertility and Skin Diseases
Some skin diseases and their treatments can negatively affect male fertility.
research A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Update on the Treatment of Alopecia Areata
Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.
research Reversal of the Hair Loss Phenotype by Modulating the Estradiol-ANGPT2 Axis in the Mouse Model of Female Pattern Hair Loss
Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.
research Evaluation of Animal Models Suitable for Hair Research and Regeneration
Animal models, especially mice, are essential for advancing hair loss research and treatment.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.