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The extracellular matrix is crucial for controlling skin stem cell behavior and health.

New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Stem cell niches are adaptable and key for tissue maintenance and repair.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Different types of stem cells and their environments are key to skin repair and maintenance.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.

When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.

CD98hc's role in skin health decreases with age.

Researchers created human hair follicles using a new method that could help treat hair loss.

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.