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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

New treatments for psoriasis have improved effectiveness and may reduce long-term side effects when combined with standard therapies.

Scalp hair grows at 0.37 mm/day, forearm hair at 0.18 mm/day, and thigh hair at 0.30 mm/day, with no significant differences found in people with certain hair conditions.

AcSDKP may help prevent skin and hair aging and promote their growth.

Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

A mix of tocopherol acetate and L-menthol helps grow hair better than using them separately or using minoxidil.

Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.

The study created a new model to better understand human hair growth and health.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.

Abemaciclib can cause skin, hair, and nail problems, leading some patients to stop using it.

Innovative methods are reducing animal testing and improving biomedical research.

Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.

Different fish use the same genes to regrow teeth.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.