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This study reported that disrupting ephrin-Eph interactions in adult mouse skin doubled cell proliferation in the hair follicle and epidermis, suggesting ephrins as negative regulators of proliferation.

This study found that ILK/ELMO2 complexes in epidermal keratinocytes are selectively activated by epidermal growth factor to induce cell migration, unlike with other growth factors.

This study suggests that stress-induced premature senescence of dermal papilla cells may contribute to hair follicle aging by impairing critical epithelial-mesenchymal interactions and promoting inflammatory cytokine production.

In this study, researchers investigated a regulatory network in cashmere goat embryos and found that fibroblast growth factor 10, alongside non-coding RNAs, significantly influences hair follicle cell proliferation, offering insights into the biology of hair follicles in cashmere goats.

This study found that BMPs can counteract the inhibitory effects of androgens on hair follicle stem cell differentiation, highlighting their critical role in the pathway dysregulation seen in androgenetic alopecia.

This study found that physoxia improved hair follicle functions in co-cultures of dermal papilla cells and melanocytes by enhancing their biological activities and promoting hair growth and pigmentation.

This study suggests that the interaction between the hairless and wise proteins can help bald mice regrow fur, highlighting its essential role in hair-follicle regeneration.

This article discusses the development and research applications of human hair follicle organ culture techniques, highlighting its potential to explore biological processes beyond dermatology.

This review examines the roles of Hyaluronic Acid and Versican in the skin extracellular matrix and reports no new research findings, highlighting their involvement in processes like differentiation and wound healing.

This study examined the molecular communication in psoriasis cells, highlighting unique immune cell interactions and identifying new features of the hair follicle cell-psoriasis axis. It suggests the potential for targeted therapies at the single-cell level to improve psoriasis treatment.

This study using scRNA-seq on 96 skin biopsies from 51 healthy individuals revealed distinct cell signaling pathways in different skin sites, including unique pathways in facial and palmoplantar skin, which may explain their varying susceptibilities to skin disorders.

This study suggests that the growth arrest of nevus melanocytes is not due to oncogene-induced senescence but rather to collective cell interactions, similar to those in normal tissue size regulation.

This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.

This study found that targeting HSP70 can suppress basal cell carcinoma growth, underscoring the importance of tumor microenvironment interactions in cancer progression.

This study found that Bone morphogenetic proteins (BMPs) play a crucial role in dermal papilla cells' ability to induce hair follicle stem cell differentiation, and that androgens may impair this process by downregulating BMPs.

This review highlights how single-cell transcriptomics has advanced understanding of tissue regeneration by revealing cellular diversity and key molecular interactions in animal models, despite methodological challenges, suggesting future applications in developing targeted regenerative therapies.

This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.

This study found that deleting the vitamin D receptor from specific stem cells in mouse hair follicles disrupts their ability to regenerate the epidermis after injury, suggesting an essential interaction with the transcription factor p63.

This review examines how regenerative therapies targeting shared biological pathways can promote healing in musculoskeletal disorders and hair follicle dysfunction, highlighting modalities like platelet-rich plasma and laser therapy while addressing challenges in standardization and measurement.

At the 21st Royan International Stem Cell Congress, researchers highlighted the growing integration in regenerative medicine, emphasizing advances in pluripotency, AI applications, and bioengineering for the development of accessible stem cell therapies.

This review summarizes how single-cell omics technologies have advanced understanding of cellular regulatory programs in sheep and goats, but highlights limitations in genomic annotation and integration with population genetics for molecular breeding.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

This study found that premature hair loss due to stress does not occur in NK-1 receptor knockout or mast cell deficient mice, suggesting a key role for neurokinin substance P and mast cell interaction in stress-related hair follicle changes.

This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.

This study characterized keratin-based biomaterials that self-assemble into hydrogels, demonstrating their potential to achieve hemostasis in a lethal liver injury model through specific biomaterial-receptor interactions.

This study reports that PADI4, an enzyme involved in posttranslational protein modifications, regulates progenitor cell transitions in hair follicle development by repressing transcription and interacting with translational and ribosomal processes.

This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.

The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.

This study identified high expression of the Sur2A subunit in cancerous cells in two animal models, highlighting a potential drug target in breast and renal cancers, with additional pharmacovigilance data linking KATP channel genes to varied cancer risks.

In this study, single-cell RNA sequencing of hair follicle populations from hidradenitis suppurativa patients identified three endotypes, suggesting distinct epithelial-immune interactions that may guide stratified therapeutic approaches.