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This systematic review found that chitosan-based wound therapy may accelerate wound healing by reducing inflammation and modulating immune response, but notes limited clinical trials to date.

This review discusses the complex correlation between cellular senescence and PCOS, emphasizing senescence markers, mechanisms, and potential anti-senescence therapies, but reports no new clinical results.

Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.

In this study, sequences upstream of the TGM3 gene were found to regulate epithelial-specific gene expression in keratinocytes, suggesting potential applications in gene therapy.

This review discusses the senescence–stemness connection in cellular biology and reports no new findings, highlighting implications for both tissue repair and aggressive cancer behavior.

Different lab conditions and light treatment methods change how human skin cells respond to light therapy.

This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.

This study concluded that stromal vascular fraction treatment was effective in increasing hair density and thickness in patients with androgenetic alopecia over a three-month period.

This study reviews lipid-based nanocosmeceuticals and reports that they enhance therapeutic effectiveness in dermatological applications by improving skin hydration, reducing wrinkles, and effectively managing conditions like psoriasis and eczema, though further large-scale trials and regulatory alignment are needed for clinical use.

This review discusses current and emerging treatments for androgenetic alopecia, covering mechanisms, efficacy, and safety of both androgen-targeted and non-androgen-targeted approaches, but reports no new clinical results.

The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.

This review discusses novel treatments for androgenetic alopecia, including therapies like platelet-rich plasma and adipose-derived stem cells, and reports no new clinical results.

p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.

This study found that the PSEN1-P242LfsX11 mutation in hidradenitis suppurativa influences cytokine and chemokine expression in macrophages, potentially affecting inflammatory responses.

This study found that transgenic cashmere goats overexpressing thymosin beta-4 have a higher secondary to primary hair follicle ratio, suggesting potential for increased cashmere yield.

This review discusses the roles of peripheral nerves in stem cell and immune responses within the skin and hematopoietic system, emphasizing their potential in developing new therapies; it reports no new experimental results.

This research observed that translation initiation shifts from cap-dependent to IRES-mediated pathways varied across tissues and cell types under stress and differentiation conditions in mice, with low IRES/Cap ratios signaling high stemness and potential multipotency, mediated by the RNA processing protein PTBP1.

In this comprehensive review, researchers examine the p63 gene's crucial role in skin development and pathology, highlighting its regulation of cell processes and its potential therapeutic implications for disorders like ectodermal dysplasia.

This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.

This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.

This review discusses recent advancements in generating appendage-bearing skin organoids from pluripotent stem cells and their potential applications in dermatological research, but reports no new clinical results.

This review describes bioengineering strategies to mimic the natural cell microenvironment in vitro, emphasizing the novel approach of using cell-synthesized extracellular matrix as a scaffold for engineering functional 3D tissues, while highlighting the limitations of exogenous scaffolds in tissue engineering.

This article outlines how nanotechnology strategies, including phospholipid-based nanocarriers like liposomes, could enhance the effectiveness and skin tolerability of acne treatments, aiming to reduce side effects and improve patient compliance in managing acne vulgaris.

This review describes recent advances in the study of epidermal stem cells and their importance in regenerative medicine and skin tissue engineering, but provides no new clinical results.

This review discusses the mechanisms of skin barrier impairment in acne vulgaris and suggests strategies for its repair but reports no new clinical results.

This study found that patients with alopecia areata had higher systemic inflammation markers compared to healthy controls, and these markers were associated with a greater risk of severe disease.

This study suggests that the herbal formulation Phyllotex™ may promote hair growth in androgenetic alopecia by enhancing cell proliferation and reducing oxidative stress and TGF-β1 expression in vitro.

This study found that in patients with alopecia areata and atopic dermatitis, 61.5% showed improvement with dupilumab treatment, but 38.5% experienced worsened or new-onset alopecia areata, with higher baseline IgE levels linked to better responses.

In this study, Quercetin-loaded black seed oil nanoemulsion effectively mitigated testosterone-induced testicular oxidative stress and inflammation in rats undergoing exercise and restraint stress, with improved antioxidant levels and reduced inflammatory markers compared to other treatment groups.

This study's network meta-analysis reported that botulinum injection combined with red laser and topical minoxidil is most effective for increasing hair density in androgenetic alopecia when using low-level laser therapy.