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This study used 3D bioprinting to implant epidermal stem cells, skin-derived precursors, and Matrigel into mouse wounds, successfully regenerating hair follicles and skin components within four weeks, with minimal impact on stem cell viability and stemness.

This study suggests that D-panthenol may promote hair growth by enhancing cell viability, suppressing apoptosis markers, and elongating the anagen phase in human hair follicle cells.

This study suggests that mesenchymal stem cell therapy may improve cell viability and regulate key signaling pathways in vitro for treating alopecia areata.

This study observed that treating basal and squamous cell carcinoma cells with platelet-rich fibrin significantly reduced cell viability and increased apoptosis-associated gene expression, suggesting potential use as adjunctive therapy for localized nonmelanoma skin cancers.

This study found that the herbal extract HX109 promoted hair growth in mice by increasing cell viability and enhancing hair regrowth, with the effects increasing as doses rose.

This review discusses various methods for processing and separating human skin samples for research purposes, evaluating factors like processing time and cell viability, but reports no new experimental findings.

This study found that Lactobacillus acidophilus cell-free supernatant caused significant cytotoxicity, reduced migratory ability, and induced apoptosis in cervical cancer cell lines, suggesting its potential as a non-toxic adjunct therapy for cervical cancer.

In this laboratory study, researchers found that a methanol extract of peach kernel improved the growth and viability of human hair follicle dermal papilla cells, suggesting its potential efficacy for hair growth and care through cell proliferation and signaling pathways activation.

This study found that Muse cells retained their pluripotency and ability to differentiate into various cell types even after being cryopreserved multiple times.

This study found that keratin coatings from human hair may improve the colony-forming efficiency of human mesenchymal stem cells by moderating donor variability, suggesting a potential use in clinical applications.

This study found that the DOX derivative AD198 more effectively inhibited cell viability and induced apoptosis in canine cancer cell lines K9TCC and K9OSA compared to DOX in vitro.

This study found that extracts from Terminalia bellirica enhanced dermal papilla cell viability, inhibited androgen-related pathways, and stimulated hair regrowth in a mouse model, suggesting potential for treating androgenetic alopecia through multi-target mechanisms.

This research found that a novel dehydroepiandrosterone derivative (12) significantly reduces cell viability and increases apoptosis in testosterone-stimulated normal and tumor prostate cells, unlike finasteride and dutasteride, which also showed activity under dihydrotestosterone stimulation.

This review highlights that exosome-based therapies show promise for hair regeneration by modulating signaling pathways and enhancing hair follicle regeneration; however, further clinical research is needed due to variability in methods and limited clinical studies.

This study found that fermented Morinda citrifolia extract enhances the viability and cycle progression of human dermal papilla cells and promotes hair growth through Wnt/β-catenin signaling activation, suggesting its potential as a therapeutic candidate for alopecia.

The systematic review reported promising outcomes for stem cell-enriched treatments in aesthetic medicine, such as improved skin rejuvenation, hair restoration, and scar revision. However, challenges like protocol variability and regulatory issues must be addressed to ensure effective and safe clinical applications.

This review reports limited evidence suggesting that stem cell-based therapies, particularly using human-derived mesenchymal stem cells and exosomes, may be effective for skin rejuvenation, though results are uncertain due to methodological limitations and variability across studies.

This study highlights the potential of stem cell-derived extracellular vesicles to treat UV-induced skin damage by modulating key signaling pathways, though challenges like EV composition variability and skin barrier penetration remain, underscoring the need for further research into optimized delivery methods for effective therapies.

In this study, injections of PRP and MZT products significantly improved hair thickness, density, and count in AGA patients over six months, with variability observed in the extent of improvement between different formulations.

This article reviews potential mechanisms by which Finasteride might enhance mesenchymal stem cell viability and differentiation post-transplant, suggesting a supportive role in myocardial infarction therapy, yet reports no clinical results.

In this study, conditioned media from stem cell-derived cardiomyocytes significantly reduced lung cancer cell viability and increased apoptosis compared to fibroblast conditioned media, suggesting its potential antitumor properties.

This study reports that in mesenchymal cells, the effect of resveratrol on cell viability and metabolic enzyme activity varied with dosage and exposure time, with high doses promoting bone differentiation and potentially benefiting mesenchymal cell health and differentiation into osteoblasts.

This literature review highlights recent advancements in hair follicle regeneration techniques, noting the potential of combining stem cell technology, 3D bioprinting, and epigenetic modulation to create precision therapies. However, it emphasizes ongoing challenges such as achieving long-term viability and scalability for clinical application.

This study confirmed porcine PRP's commercial viability as a fetal bovine serum replacement, showing higher growth factor levels and stability, without increasing human follicle dermal papilla cell proliferation compared to FBS.

This study found that overexpressing FGF22 in dermal papilla cells enhanced hair follicle stem cell proliferation and viability, while its knockout reduced these attributes, indicating its role in hair follicle regeneration.

This study found that a keratin film made from human hair supports enhanced cell proliferation and viability compared to collagen I, suggesting potential for cell culture applications.

This review analyzes the impact of different preparation methods for platelet-rich plasma, human follicles stem cells, and adipose-derived stem cells on hair regrowth and wound healing, but reports no new results; the authors emphasize convincing evidence of positive outcomes despite protocol variability.

This study explored how high glucose concentrations impact mesenchymal stromal cell survival in diabetic environments, highlighting mitochondrial factors as potential targets for enhancing cell viability.

In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.

This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.