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Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Apoptosis is essential for human skin development and forming a functional epidermis.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Understanding where cancer cells come from helps create better prevention and treatment methods.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Both mouse and rat models are effective for testing alopecia areata treatments.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Signaling pathways are crucial for hair growth in goats.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

The skin and thymus develop similarly to protect and support immunity.

A pulsed electrical field safely and effectively increased hair growth.

Loose Anagen Syndrome causes easy-to-pull, thin hair, mainly in young girls, and improves with age.

NFIC helps human dental stem cells grow and become tooth-like cells.

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

MED1 affects skin wound healing differently in young and old mice.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Telocytes in the scalp may help with skin regeneration and maintenance.