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Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Thymosin β4 helps improve skin healing and reduce scarring.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Growth factors are crucial for hair development and could help treat hair diseases.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Researchers found 24 genes that change significantly and affect cashmere growth in goats; this could help increase cashmere production.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.