Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, Agaricus bisporus derived β-Glucan particles demonstrated antimicrobial, antioxidant, and anticancer effects against cervical cancer HeLa cells, suggesting potential as a therapeutic option.

The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.

This study found variable outcomes in hair loss treatment with autologous cell-based therapy using DSC cells, with certain gene markers showing inconsistent correlations with treatment efficacy.

This study found that upregulated miR-149 restricted hair follicle stem cell differentiation and hair growth by inhibiting the MAPK1/ERK2 pathway, which affects FGF2 and c-MYC expression.

This study found that injectable platelet-rich fibrin (i-PRF) enhances hair follicle regeneration in vitro by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity, with varying effects depending on concentration.

In this study, researchers found that treating dermal papilla cells with synovial fluid and laser photobiomodulation increases the expression of chondrocyte marker genes, indicating potential promotion of chondrogenic differentiation.

This study found that overexpression of Gasdermin A3 in mice disrupts the hair follicle stem cell niche and causes hair loss through cell necrosis and abnormal hair cycle progression, without involving immune-mediated mechanisms.

This study found that higher doses of zinc increased cell growth but also induced cell death in human follicle dermal papilla cells, suggesting a narrow dosage range may affect hair regrowth.

This study found that 70% ethanol extract of Houttuynia cordata promoted hair growth in laboratory cell models, suggesting potential use in developing hair care products.

This study used two-photon microscopy to reveal that the dermal papilla is crucial for hair follicle regeneration and cannot be replaced by neighboring cells, providing new insights into stem cell behavior.

This study reveals that the microRNA-200 family, highly enriched in hair matrix progenitors, restricts sebaceous gland development by inhibiting the SOX9-dependent lipogenic program, highlighting its specific role in epithelial plasticity within hair follicles.

This study observed that, in mouse ear epidermal stem cells, a cell-autonomous size control mechanism involving the RB pathway dictates S phase entry timing based on cell size, despite external environmental variations affecting growth rates.

This study found that RSPO1, a Wnt/β-catenin pathway agonist, significantly induces insulin-producing β cell replication and neogenesis in various settings, offering a promising potential therapy for diabetes.

This study found that implanting hair-follicle-associated pluripotent stem cell sheets in mice significantly accelerated wound closure and reduced scar formation compared to non-implanted controls.

This study suggests that supplementing with a cell-free fat extract might enhance embryo development and improve clinical outcomes in older women experiencing in vitro fertilization failure.

In a rat skin wound model, this study observed that a composite dressing using chitosan hydrogel and exosomes derived from adipose mesenchymal stem cells enhanced wound healing by promoting collagen deposition, angiogenesis, and regeneration of hair follicle structures.

This study found that fibronectin-attached cell sheets significantly improved wound healing in vivo by increasing wound closure rates, reducing inflammation, and promoting tissue regeneration compared to conventional cell sheets.

This study found that washing hair with surfactants reduces the internal density of hair due to cuticle lifting, and suggests that a cuticle-sealing strategy can inhibit this effect and maintain hair homeostasis.

In this study, MSC-derived magnetic nanovesicles combined with a magnetic field increased skin retention and accelerated hair follicle growth in a mouse model of hair regeneration.

This study found that deleting the vitamin D receptor from specific stem cells in mouse hair follicles disrupts their ability to regenerate the epidermis after injury, suggesting an essential interaction with the transcription factor p63.

In this study, researchers found that Wnt4 overexpression increased the thickness of burn wounds by promoting epidermal cell migration and activating the canonical Wnt signaling pathway.

This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.

This study found that Y27632 treatment facilitated the formation of core-shell-shaped hair follicle organoids, resulting in nearly 100% efficient hair shaft sprouting in vitro.

This study found that SMAD2 overexpression in human hair follicle stem cells promoted differentiation and apoptosis while inhibiting proliferation, and Smurf2 upregulation limited mouse wound healing by suppressing the SMAD2/NANOG/DNMT1 axis.

This study found that CRISPR/Cas9 efficiently edited two cellulose synthase-like genes in spinach, significantly altering root hair growth patterns and suggesting potential for large-scale genome editing in this crop.

This study found that injury-induced proliferation of wild-type cells can suppress oncogenic growth in Ras-mosaic skin.

In this study, Fgf20 was found to trigger movement and morphogenesis in dermal fibroblasts, facilitating dermal condensate formation essential for hair follicle development.

This study identified a proliferative intermediate transcriptional state associated with the transition from secondary hair germ cells to lower hair follicle-associated cells during early hair follicle regeneration in mice.

This study found that ACOD1 deficiency in dermal papilla cells promotes mitochondrial dysfunction and contributes to cellular senescence in androgenetic alopecia, suggesting ACOD1 as a potential therapeutic target and 4-octyl itaconate as a promising treatment option for AGA.

This study found that plucked hair follicles can serve as a practical and scalable source for regenerative medicine, as researchers successfully isolated and expanded keratinocytes and mesenchymal stem cells for potential cell-based and cell-free therapies, demonstrating significant wound-healing bioactivity in vitro.