4 citations
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January 2013 in “International Journal of Trichology” This study found that the distribution of desmogleins is associated with specific types of keratinization and hair anchorage, as well as hypotrichosis.
3 citations
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July 2022 in “Brain and Behavior” This study observed that a CARASIL mouse model demonstrated abnormal behavior, vascular and cellular changes, and upregulation of the TGF-β/Smad signaling pathway, indicating its potential involvement in CARASIL pathogenesis.
3 citations
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September 2005 in “International Journal of Cosmetic Science” This study found that monounsaturated oils like olive oil penetrate hair fibers effectively, whereas polyunsaturated oils typically do not penetrate beyond the cuticle.
2 citations
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December 2023 in “Advanced science” This review discusses the roles and mechanisms of glycosaminoglycans in wound healing and presents challenges and potential applications for GAG-based biomaterials without reporting new experimental results.
2 citations
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December 2022 in “Journal of Biochemistry and Molecular Biology” This review discusses the development and potential applications of organoids for human disease modeling and regenerative medicine but reports no new experimental results.
2 citations
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May 2022 in “Research Square (Research Square)” This study demonstrates that the amino-terminally shortened KGF-1 variant with 135 residues maintains biological activity, suggesting it may serve as an alternative to the original KGF-1 for certain therapeutic applications.
1 citations
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December 2023 This study explored the complex developmental processes of human hair, emphasizing the intricate interactions required for hair follicle morphogenesis and its implications for drug incorporation and concentration interpretation, particularly in early childhood.
1 citations
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October 2022 in “JCI insight” In this study, conditional deletion of BRD4 in OX40-expressing cells of mice led to alopecia, dermatitis, and loss of hair follicle stem cell function, revealing BRD4's role in skin inflammation and stem cell regulation.
1 citations
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January 2019 in “Archives of Clinical and Medical Case Reports” In this study, researchers identified two mechanisms of lipid loss from hair when exposed to surfactants, with the mechanism depending on the lipid's hydrophobicity.
1 citations
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April 2001 in “Biological Rhythm Research” This study suggests that D2O increases hair length in nude mice by extending the hair cycle duration, particularly the hair-existing phase, which is associated with increased mast cell density.
1 citations
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January 2001 in “PubMed” This study proposes that the terminal tuft structure in sensory nerve endings, involving Schwann cell processes and axon fingers, potentially plays a role in mechano-electric transduction in rats.
1 citations
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January 1997 in “Dialnet (Universidad de la Rioja)” This review discusses recent advancements in understanding how the extracellular matrix regulates epidermal stem cell fate and highlights the significance of ECM in stem cell maintenance and differentiation, with implications for regenerative medicine.
August 2026 in “The Journal of Dermatology” In this review, the authors summarize recent findings on dermal white adipose tissue (dWAT), highlighting its crucial role in the hair follicle microenvironment by regulating inflammation and immune responses, thus influencing hair regeneration.
April 2026 in “Biomedical and Biotechnology Research Journal (BBRJ)” In this study, researchers observed that using microtube-based forced aggregation, human hair follicle dermal papilla cells formed stable, compact spheroids at higher cell densities, showing enhanced expression of specific markers compared to 2D culture.
January 2026 in “Minia Journal of Medical Research” In this study, testosterone-induced alopecia in male rats led to significant thinning and follicular degeneration, but treatment with adipose-derived stromal vascular fraction cells markedly improved these histological changes, suggesting a potential role in hair follicle regeneration.
November 2025 in “Chemistry - An Asian Journal” This perspective reviews enzyme-instructed self-assembly (EISA) as a conceptual framework for supramolecular chemical biology, emphasizing its innovative role in developing adaptive biomaterials and synthetic cellular machines without providing new experimental results.
June 2024 in “Synthetic and systems biotechnology” In this study, researchers identified a collagen fragment, sample-1707, expressed in E. coli, which forms nanofibers and promotes blood clotting, osteoblast differentiation, and skin cell regeneration, making it a promising biomaterial for skin care, with a large-scale production yield of 600 mg/L.
January 2024 in “Journal of tissue engineering” In this study, researchers used a human skin organoid model to show that solar UV exposure damages hair follicles and skin, while exosomes from mesenchymal stem cells reduced inflammation and supported hair follicle regeneration.
January 2024 in “Biomaterials Research” This study found that human hair follicle dermal papilla cells cultivated as 3D spheroids in hexanoyl glycol chitosan-coated dishes formed hair-like structures, with minoxidil enhancing growth, and successfully integrated into artificial skin models, suggesting advancements for hair loss treatments and skin restoration therapies.
October 2023 in “Bioactive Materials” This study developed a novel liposome-based delivery system for Minoxidil and nitric oxide, which showed promising results in promoting hair regrowth in an androgenetic alopecia model by enhancing transdermal absorption, prolonging skin retention, and reducing inflammation.
This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.
September 2019 in “Journal of Investigative Dermatology” This study found that a new formulation using short chain esters and ethanol can selectively deliver hydrogen peroxide to hair follicles during epilation, causing follicular damage without affecting epidermal keratinocytes.
April 2018 in “Journal of Investigative Dermatology” This study found that desmosomal cadherin desmoglein 3 loses its rigidity upon Ca2+ removal, regardless of desmosome functional state, suggesting a central role for signaling in hyper-adhesion.
This thesis explores how optical coherence tomography and advanced imaging methods may address clinical needs in fields like interventional pulmonology and dermatology, highlighting their potential for disease assessment and staging.
This review discusses the roles and characteristics of skin stem cells, their niches, and signaling pathways in skin maintenance, aging, and cancer, highlighting their potential in therapeutic applications but presenting no new clinical findings.
July 2016 in “Indian journal of science and technology” In this study, researchers found that neonate hairs have a distinct microstructure with no medulla and smaller hair follicles compared to adult hairs.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that targeting the tumor stroma to promote the formation of dermal condensates may offer a novel approach to treating basal cell carcinoma.
This review explains that linoleic acid deficiency can lead to skin and growth issues but notes that such deficiencies are rare in well-nourished Western populations; it reports no new clinical findings.
January 1981 in “Purdue e-Pubs (Purdue University)” This study observed that the pig integument is similar to human skin in both light and electron microscopy, with minimal postnatal developmental differences noted.