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High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.

Dermal adipose tissue in mice can change and revert to help with skin health.

SOX9 is essential for the development of various organs and hair follicles.

The new microwell device helps grow more hair stem cells that can regenerate hair.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.

A new 3D culture system helps grow and study mouse skin stem cells for a long time.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.

Different types of skin fibroblasts have unique roles in skin health and disease.

JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.

Hoxc genes control hair growth through Wnt signaling.

Hair growth and development are controlled by specific signaling pathways.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Targeting TGFβ can improve skin immunity in older people.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.

Skin organoids from stem cells could better mimic real skin but face challenges.

Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.

Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Cilostazol may help hair grow and could be a new treatment for hair loss.

Certain microRNAs may protect against hair loss in alopecia areata and could be potential treatment targets.