14 citations,
February 2020 in “Scientific reports” Telocytes in the scalp may help with skin regeneration and maintenance.
11 citations,
March 2014 in “Journal of Investigative Dermatology” Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
6 citations,
June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
5 citations,
April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
4 citations,
September 2017 in “Skin appendage disorders” The dog with an Alopecia Areata-like condition showed signs of an autoimmune disease and partially regrew hair without treatment, suggesting dogs could be models for human AA research.
1 citations,
March 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The hair treatment made hair grow faster and thicker and strengthened the hair roots.
1 citations,
May 2017 in “InTech eBooks” Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
1 citations,
June 2016 in “FEBS open bio” Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.
1 citations,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
January 2012 in “Methods in pharmacology and toxicology” TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
172 citations,
March 2019 in “The EMBO Journal” FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.
77 citations,
July 2020 in “European Journal of Clinical Pharmacology” Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
28 citations,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
7 citations,
January 2015 in “Hair therapy & transplantation” Air pollution can cause hair loss, and using antioxidants, special shampoos, and coconut oil can improve scalp health and hair density.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
October 2017 in “Journal of The European Academy of Dermatology and Venereology” Stem cells preservation in AGA could be a potential therapy, but more cases needed.
7 citations,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
131 citations,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
81 citations,
September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
29 citations,
March 2014 in “PloS one” Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.
21 citations,
November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
3 citations,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
408 citations,
January 2017 in “Science” Some wound-healing cells can turn into fat cells around new hair growth in mice.
82 citations,
July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
59 citations,
November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
43 citations,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
18 citations,
March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
13 citations,
November 2017 in “Neurotoxicity research/Neurotoxicity resarch” Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.
1 citations,
July 2018 in “Elsevier eBooks” Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.