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The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Inhaling medicine may reduce side effects and improve treatment for a major lung cancer type.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.

Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.

iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.

New drug delivery methods can make natural compounds more effective and stable.

New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.

Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.