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Ganoderma lucidum extract may help treat stress-related hair loss.

In this study, researchers found that alopecia areata patients show a significant reduction in suppressive regulatory T-cells and an increase in inflammatory T-cell populations, suggesting an immunological imbalance contributing to the disease.

This study describes a new method for isolating intact human eccrine glands from scalp follicular units, potentially advancing research on sweat gland physiology.

In this study, researchers observed that activated platelet-rich plasma promoted hair growth in mice and increased cell proliferation in vitro, suggesting potential clinical applications for hair growth treatment.

In this study, researchers used transcriptomics and modeling to uncover previously unknown cell populations and marker genes in developing hair follicles, providing insights into early cell fate establishment and offering tools for further research on skin appendages.

This study found that ATM protein plays a crucial role in protecting human hair follicle melanocytes from oxidative stress, which is linked to the greying of hair.

In this study, researchers mapped gene expression in developing hair follicles to reveal unknown cell populations and markers, suggesting early establishment of cell fates in hair placodes.

This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.

This study identified 63 genetic loci associated with male-pattern baldness, uncovering genes and pathways that may help develop treatments and suggesting its connection to other human conditions.

This study found that the vitamin D receptor is essential for the self-renewal, migration, and differentiation of epidermal stem cells during skin wound healing in mice.

This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.

This study found that Wnt ligands from CD133-positive dermal papilla cells are essential for maintaining hair growth by supporting cell signaling between different hair follicle structures.

This study observed that dermal papilla cell aggregates showed increased viability and gene expression on softer 3D substrates, indicating the importance of substrate stiffness in cellular behavior.

This study found that Kangfuxin improved cell proliferation, migration, and wound healing in a mouse model of cutaneous injury through the activation of the STAT3 signaling pathway.

In this study, hair follicle-derived mesenchymal stromal cells showed potential for immunomodulation, with equivalent or superior responses compared to those from adipose tissue, suggesting a promising alternative cell source.

This article reviews the autoimmune mechanism and potential environmental triggers of alopecia areata, focusing on cytokines, but does not provide new research findings.

This study found that in individuals with androgenetic alopecia, the expression of apoptosis-related markers differed significantly between affected and unaffected scalp areas.

This study explored the effects of red ginseng-derived components on aging skin cells and found they do not have senolytic properties but can alleviate signs of cellular aging and improve skin cell function by reducing senescence markers and inflammation.

Wnt and SHH signals together influence hair follicle cell development, offering insights for hair loss treatment.

This study found that oral administration of Terminalia bellirica enhanced hair growth in testosterone-suppressed conditions in both human cell and mouse models, outperforming finasteride, a current commercial hair loss treatment.

In this study, researchers explored the heterogeneity of pigment cells in the human scalp anagen hair follicle bulb and discovered unexpected subpopulations of melanocytes, including immature SOX10-negative cells, highlighting potential non-melanogenic roles or transitional migratory functions that require further investigation.

This study found that conditional deletion of CD271 in mouse epidermis led to significant disorganization and increased thickness, suggesting CD271's crucial role in regulating skin differentiation and structure.

In this study, Wang et al. (2022) found that in patients with cutaneous lupus erythematosus, chronic lesions contained more senescent progenitor cells, marked by p16 and p21, than subacute lesions, suggesting a link between disease chronicity and cellular senescence.

This study identified a genetic locus associated with rhabdomyosarcoma susceptibility in mice and found that specific differentiation markers are linked to the regression of basal cell carcinoma.

This study found that both Th1 and Th2 cytokine markers were elevated in the serum and skin of patients with alopecia areata, with Th2 markers more closely linked to disease severity.

This study found that SM04755, a novel topical drug, inhibited inflammation, keratinocyte proliferation, and fibrosis in vitro and improved skin health in a mouse model of psoriasis, indicating potential as a topical psoriasis treatment.

This study found that basal cell carcinoma exhibits patterns of hair follicle differentiation but is stuck in telogen arrest, which can be rescued by adding noggin and TGF-β2 in vitro.

This study found that manipulating both gene expression and matrix stiffness in mice can alter hair regeneration after skin wounding, highlighting key factors in regenerative biology.

This study suggests that keratin 15 and Id3 proteins play distinct roles in epithelial and dermal cell activities during the regeneration stages of rat vibrissae hair follicles.

In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.