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    Glossary Cell Differentiation

    process where cells become specialized in structure and function

    Cell differentiation is the process by which a less specialized cell becomes a more specialized cell type, acquiring distinct structures and functions. This is crucial for the development of multicellular organisms, allowing cells to form tissues and organs with specific roles, such as skin cells, muscle cells, or neurons.

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    Research 30 of 1000+

    1. Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    2. Nestin is a marker of unipotent embryonic and adult progenitors differentiating into an epithelial cell lineage of the hair follicles Scientific reports · 2022 · 1 citations
    3. Intrinsic activation of cell growth and differentiation in ex vivo cultured human hair follicles by a transient endogenous production of ROS Scientific reports · 2019 · 9 citations
    4. Cytokeratins as Markers of Follicular Differentiation American Journal of Dermatopathology · 2001 · 121 citations
    5. Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells BioMed research international · 2014 · 10 citations
    6. Neutrophil gelatinase‐associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin Experimental dermatology · 2002 · 96 citations
    7. 576 A preliminary study of melanogenic markers in the differentiation of the human hair follicle melanin unit 2022
    8. Abstract 5219: The role of MEK and Antizyme in keratinocyte stem cell expansion and differentiation Cancer Research · 2012 · 1 citations
    9. Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors Journal of Investigative Dermatology Symposium Proceedings · 2001 · 73 citations
    10. LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants Journal of Investigative Dermatology · 2025
    11. Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs 2021 · 12 citations
    12. Basal cell carcinoma possibly originates from the outer root sheath and/or the bulge region of the vellus hair follicle Archives of Dermatological Research · 1999 · 107 citations
    13. Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor 2015 · 31 citations
    14. Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro Experimental Cell Research · 2015 · 24 citations
    15. Culture Strategy Determines the Differentiation Status of Sweat Gland Cells Cells · 2025
    16. Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture Scientific reports · 2022 · 2 citations
    17. Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation International journal of oncology · 2009 · 8 citations
    18. Gene Expression Analysis of Chondrogenic Markers in Hair Follicle Dermal Papillae Cells Under the Effect of Laser Photobiomodulation and the Synovial Fluid Journal of lasers in medical sciences · 2019 · 2 citations
    19. Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair 2018 · 46 citations
    20. 889 Trpv3 gain-of-function mutation impairs differentiation of hair follicle inner root sheath 2019
    21. Defining and targeting differentiation of non-melanoma skin cancer 2014
    22. Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells 2016 · 6 citations
    23. Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro Molecular Medicine Reports · 2017 · 5 citations
    24. CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties PLOS genetics · 2019 · 41 citations
    25. Twist1 is required for the development of UVB‐induced squamous cell carcinoma Molecular Carcinogenesis · 2021 · 11 citations
    26. Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin and the phorbol ester 12-<i>O</i>-tetradecanoylphorbol-13-acetate Carcinogenesis · 1987 · 12 citations
    27. Organotypic Cocultures as Models to Study Cell-Cell and Cell-Matrix Interactions of Human Hair Follicle Cells Skin Pharmacology and Physiology · 1994 · 18 citations
    28. 8280186 Biomarkers for Occupational Hand Eczema: Improving Diagnostic Differentiation 2025
    29. Defining the complex epithelia that comprise the canine claw with molecular markers of differentiation Veterinary Dermatology · 2009 · 6 citations
    30. 1360 Fate tracing of DNA-damaged hair follicle stem cells and their seno-differentiation clearance out of the niche 2023