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Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Blocking JAK-STAT signaling can lead to hair growth.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Active transdermal technologies in cosmetics help deliver skin treatments effectively, but their safety and effectiveness depend on skin type and treatment choice.

AcSDKP may help prevent skin and hair aging and promote their growth.

Androgens can both increase body hair and cause scalp hair loss.

Activating TLR3 may help produce retinoic acid, important for tissue regeneration.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

The OVOL1-OVOL2 axis is important for hair follicle differentiation and can help diagnose certain hair-related tumors.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Skin fat helps with body temperature control and has other active roles in health.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.