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Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Active transdermal technologies in cosmetics help deliver skin treatments effectively, but their safety and effectiveness depend on skin type and treatment choice.

RNA from horse hair follicles can track circadian rhythms non-invasively.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

The document explains the genetic causes and characteristics of inherited hair disorders.

The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

Ayurvedic herbs may reduce side effects and improve effectiveness of cancer treatments.

Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.

DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.

Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.