132 citations,
November 1998 in “Journal of the American Academy of Dermatology” Topical sensitizers have mixed success in treating alopecia areata.
62 citations,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
61 citations,
August 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
43 citations,
December 2017 in “BMC Plant Biology” GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.
36 citations,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
32 citations,
February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
28 citations,
September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
26 citations,
October 2016 in “American journal of clinical dermatology” New treatments like JAK inhibitors show promise for reversing alopecia areata.
20 citations,
March 2021 in “Drug design, development and therapy” Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.
19 citations,
June 2021 in “The world journal of men's health” Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.
19 citations,
March 2016 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
13 citations,
January 2015 in “International Journal of Trichology” Higher lead and cadmium, and lower zinc and iron levels in the blood might be linked to chronic hair loss in women.
11 citations,
January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.
11 citations,
July 2021 in “Genetics selection evolution” Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.
10 citations,
August 2021 in “Cosmetics” The best shampoo formula used 1% high-weight hyaluronic acid, 10% acidic sophorolipid, and 1% salt for effective hair conditioning and cleansing without sulfates or silicones.
9 citations,
January 2023 in “Phytomedicine” More high-quality research is needed to recommend flavonoids and saponins for clinical use.
9 citations,
April 2018 in “Biology of reproduction” Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
9 citations,
January 2013 in “International journal of trichology” 88% phenol is effective for treating alopecia areata.
5 citations,
July 2019 in “Nutrients” Low selenium intake may delay puberty in boys but not in girls.
4 citations,
October 2022 in “Journal of Imaging” An intelligent system can classify hair follicles and measure hair loss severity with reasonable accuracy.
4 citations,
October 2021 in “Microorganisms” The study analyzed the scalp microbiome and sebum composition of 118 Japanese males, comparing those with androgenetic alopecia (AGA) to those without. It found that individuals with AGA had higher levels of sebum triglycerides and palmitic acid, and their fungal microbiome was dominated by Malassezia restricta. The bacterial microbiome in AGA patients showed increased Cutibacterium and decreased Corynebacterium, indicating scalp dysbiosis. These findings suggest that both sebum composition and microbial imbalances may play roles in the development of AGA.
3 citations,
February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine” A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
2 citations,
May 2022 in “International journal of molecular sciences” Changes in KRT17 gene activity linked to wool production in Angora rabbits.
2 citations,
September 2021 in “Orphanet Journal of Rare Diseases” People with hypohidrotic ectodermal dysplasia are more likely to experience long-term fatigue and hair loss after COVID-19.
1 citations,
September 2023 in “Molecules (Basel. Online)” Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.
1 citations,
August 2023 in “Military Medical Research” Smart hydrogel dressings could improve diabetic wound healing by adjusting to wound conditions and controlling drug release.
1 citations,
March 2023 in “Nutrients” The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
1 citations,
January 2023 in “Indian dermatology online journal” Many people use home remedies for skin conditions, but there's limited scientific evidence to support their effectiveness.
1 citations,
January 2022 in “Health” COVID-19 has widely affected health, various industries, and the economy, but also led to more remote work and less pollution.
1 citations,
December 2021 in “Animals” Low zinc and selenium levels in sheep are linked to hair loss and thyroid problems.