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This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.

This study demonstrates that encapsulating cell-free fat extract in a gelatin methacrylate hydrogel enhances flap repair by sustaining angiogenesis, reducing oxidative stress, and offering favorable biocompatibility in a murine skin flap model, thereby advancing potential clinical flap necrosis treatments.

This study introduces Cell Journey, a new platform for visualizing RNA velocity in 3D, which aims to better capture complex cellular transitions in single-cell datasets compared to current 2D methods.

In this review, researchers summarize key factors in constructing skin organoids, including cell source and assembly methods, and emphasize advances such as air-liquid interface culture for improving tissue development, aiming to guide standardized protocols and future clinical applications.

This review suggests that induced pluripotent stem cells (iPSCs) hold promise for treating chronic wounds, but further work is needed to address safety, efficacy, and translation from preclinical models to real-world applications.

This study experimentally validated Lockhart's viscoplastic framework for tip growth in Arabidopsis root hairs by demonstrating alignment with observed growth rates and estimating yield turgor pressure and cell wall viscosity, offering a methodology adaptable to other species and conditions.

In this laboratory study, the researchers found that combining dermal papilla cell-derived exosomes with collagenous sequences significantly enhanced hair follicle stem cell migration and proliferation, highlighting a potential strategy for hair regeneration through modulation of the hsa-novel-238a-CASP9 axis.

This study found that conditioned medium from human dental pulp stem cells (particularly under hypoxic conditions) improved keratinocyte survival and hair regrowth in a chemotherapy-induced alopecia mouse model and did not promote tumor growth, suggesting potential for safe therapeutic use.

This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.

This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.

This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.

This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.

This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.

This review discusses the various applications of chitosan-based materials in dermatology and highlights their potential as promising new materials but does not present new experimental results.

In this controlled study, a pulsed electrical field treatment significantly increased hair regrowth compared to baseline and the control group over 36 weeks, without observed side effects.

This perspective highlights how advancements in single-cell sequencing and digital pathology can help understand the complex mechanisms of immune responses, fibrosis, and tissue remodeling related to medical implants, aiming to address the challenges of implant-related tissue reactions reported in this study.

This review discusses the potential of exosome therapy for treating diabetic peripheral neuropathy but highlights the need for more robust preclinical trials before clinical application.

The researchers developed a comprehensive human skin cell atlas using data from various studies and established a consensus nomenclature for normal human skin in this project, which also includes a deep learning-based method for more effective reference mapping of new cells.

This review discusses various nanoparticles and nanoemulsions being investigated for transdermal drug delivery and reports no clinical results; it highlights potential applications in treating alopecia, wound healing, psoriasis, and melanoma.

This review outlines the advancements in organ and tissue transplantation since the discovery of the human MHC and reports no new clinical results.

This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.

This review discusses the structure and regenerative potential of hair follicles, highlighting their role in wound healing, stem cell populations, and keratin-based biomaterials, but it reports no new clinical results.

In this study, a UK expert panel discussed strategies for managing common side effects of vismodegib, a hedgehog pathway inhibitor used for advanced basal cell carcinoma, concluding that adverse events like taste disturbances and muscle cramps can be effectively managed to optimize treatment duration.

This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.

This review discusses the use of stem cells and stem cell-derived products in burn wound healing, highlighting various stem cell sources, associated signaling pathways, and delivery methods, but reports no new clinical results.

This article discusses recent advancements in treatments for psoriasis, including new drug approvals and innovative therapeutic approaches, but reports no new clinical results.

This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.

This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.

In this study, TC-1 cells, resembling stromal cells formed by epithelial-mesenchymal transition, significantly affected the behavior of normal human keratinocytes, supporting the role of stromal cells in tumor progression.

This review highlights that the RNA modification N⁶-methyladenosine (m⁶A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.