September 2024 in “Turkish Journal of Dermatology” In this study, researchers found that males with alopecia areata had a significantly lower 2D to 4D finger length ratio compared to healthy controls, suggesting this ratio might predict alopecia areata development, though it did not correlate with disease severity.
This study developed a topical dutasteride-loaded Insitu-emulgel for treating androgenetic alopecia, finding it effectively controls drug release, enhances skin penetration, and may improve patient compliance compared to traditional topical treatments, though further clinical research is underway.
February 2024 in “Research Square (Research Square)” In this study, researchers applied Strat-M® membrane to assess the in vitro transdermal properties of collagen peptides, finding a high correlation with results from mouse skin and suggesting that Strat-M® can effectively replace excised mouse skin in transdermal experiments.
January 2024 in “Journal of Cosmetics Dermatological Sciences and Applications” This study investigated the safety and effectiveness of two thioglycolate chemical depilatory creams for full genital hair removal in men and women, finding acceptable dermal tolerance despite some instances of irritation, supporting their use for pubic hair grooming.
January 2023 in “Nanomedicine & nanotechnology open access” This review suggests that microneedling shows promise for improving hair quality, thickness, and density in treating androgenetic alopecia, but standardized treatment protocols are currently lacking.
November 2021 in “International journal of life science and pharma research” This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.
February 2015 in “Journal of Biomedical Materials Research Part B: Applied Biomaterials” This study suggests that 4-META resin may be more effective than cyanoacrylate for promoting wound healing in rats, as the wounds were covered by epithelial tissue faster with 4-META resin.
June 1998 in “Biomedicine & Pharmacotherapy” This document by the AACE and AES provides a 2015 summary of best practices for diagnosing and managing PCOS, emphasizing clinical assessment and treatment options but reports no new clinical results.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.
74 citations
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September 1980 in “Medical Clinics of North America” This article discusses toxic epidermal necrolysis, highlighting its high mortality rate despite aggressive treatment, and notes controversy over using high-dose systemic corticosteroids as therapy.
68 citations
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April 2002 in “Journal of Human Nutrition and Dietetics” This study found that although diabetic patients undergoing a very low calorie diet experienced faster weight loss initially, those on a conventional diet and exercise plan maintained weight loss more effectively over five years.
38 citations
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June 2018 in “Archives of Toxicology” This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.
15 citations
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May 1997 in “Annals of Internal Medicine” This case report describes a patient with breast cancer who developed female androgenetic alopecia after starting tamoxifen therapy.
13 citations
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September 2021 in “Communications Biology” This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.
12 citations
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October 2016 in “Anais Brasileiros de Dermatologia” This review discusses the increasing reports of frontal fibrosing alopecia, a form of scarring alopecia, and its potential link to autoimmune disorders, but reports no new clinical results.
10 citations
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September 2020 in “Metabolites” This study found that metabolite levels in hair samples differ significantly by hair color and segment, leading to recommendations for best practices in hair metabolomic studies.
6 citations
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January 2016 in “International Journal of Andrology” In this study, researchers found an inverse association between baldness and testicular cancer, suggesting androgen activity may influence cancer risk.
This study found that patients with androgenetic alopecia showed distinct scalp bacterial imbalances compared to healthy individuals, which were associated with unhealthy lifestyles. These microbial changes might contribute to follicular inflammation, potentially accelerating hair loss in these patients.
June 2026 in “International Science Journal” This study reviewed recent advances in regenerative technologies for aesthetic and reconstructive medicine and found that adipose-derived stem cells and platelet-rich plasma are well-established for tissue repair due to their safety and effectiveness, while emerging technologies like exosome-based therapies hold future potential.
February 2026 in “Cureus” In this narrative review, the authors compared monotherapy and combination therapy for type 2 diabetes, finding that while monotherapy is effective in early stages, combination therapy offers superior glycemic control and cardiovascular benefits, though it requires individualized selection for safety and adherence.
February 2026 in “Plastic and Aesthetic Research” This narrative review examines advancements in regenerative aesthetic medicine, focusing on injectable modalities like PRP, polynucleotides, and exosomes, but highlights the need for more robust evidence and standardization in clinical applications.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This review highlights the significant psychosocial impact of alopecia areata on children and adolescents, affecting self-esteem, relationships, academic performance, and the well-being of their families.
August 2025 in “International Journal of Research in Dermatology” This review systematically analyzed 22 clinical trials on hair care, finding that while most studies employed appropriate statistical methods, significant inconsistencies in reporting test assumptions and effect sizes may hinder reproducibility, highlighting a need for better standardization and transparency in these research practices.
June 2025 in “Medical & Clinical Case Reports Journal” This systematic review concludes that exosomes may offer significant therapeutic potential for treating androgenetic alopecia, with observed improvements in hair density and follicular health, but further long-term clinical studies are necessary for validation.
January 2025 in “MEDS Public Health and Preventive Medicine” In this study, oral spermidine supplementation was found to significantly prolong the hair follicle anagen phase and reduce hair loss, with effects persisting three months after treatment in healthy participants, suggesting potential therapeutic benefits for hair loss conditions.
March 2024 in “Research Square (Research Square)” This study found no significant benefit of platelet-rich plasma injections over placebo in improving erectile function in patients with mild to moderate erectile dysfunction.
The study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in HUVECs, with early pregnancy cells showing more significant effects than those from full-term pregnancy.
26 citations
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June 2020 in “Polymers” This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.
4 citations
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July 2025 in “International Journal of Nanomedicine” This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.
4 citations
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January 2025 in “Journal of Materials Chemistry B” In this study, researchers developed a multifunctional, injectable hydrogel that adapts to irregularly shaped wounds, enhances healing, and shows potential antibacterial activity without significant toxicity, suggesting promise for treating chronic wounds.