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Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Excess androgens may cause PCOS, not just be a symptom.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Eclipta alba extract may help treat obesity by blocking fat cell formation and lowering blood lipid levels.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Blocking JAK-STAT signaling can lead to hair growth.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Fat cells in the skin help start healing and form important repair cells after injury.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Skin fat helps with body temperature control and has other active roles in health.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Cell aging can be both good and bad for tissue repair.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.