This study found that pediatric alopecia areata patients had significantly lower serum BDNF levels compared to healthy controls, which were associated with greater alopecia severity, higher depressive symptoms, and poorer quality of life.
3 citations
,
August 2020 in “Journal of The American Academy of Dermatology” This study observed that patients with scalp dysesthesia frequently exhibited cervical spine degenerative changes, which localized predominantly in the lower cervical spine, and reported modest symptom improvement with neuropathic pain medications and physical therapy.
2 citations
,
July 2025 in “Scientific Reports” In this study, researchers found that dermatological diseases like atopic dermatitis, psoriasis, and hidradenitis suppurativa impact women's work performance and daily activities more severely than men's, with women reporting higher absenteeism and work impairment and lower work ability scores.
43 citations
,
March 2011 in “Journal of psychosomatic research” This study found that children with alopecia areata experienced more stressful life events and excreted higher levels of catecholamines compared to healthy siblings.
2 citations
,
October 2022 in “Frontiers in genetics” This case report describes a 46-year-old Italian woman with congenital adrenal hyperplasia who experienced significant improvements in physical and psychological health after receiving a delayed diagnosis and subsequent treatment.
14 citations
,
February 2018 in “Psychoneuroendocrinology” This study found that male 5α-reductase 2 knockout mice showed deficits in social dominance behaviors and reduced dopamine receptor binding in a brain region related to social ranking.
April 2025 in “International Journal of Multidisciplinary Research in Science, Engineering and Technology.” In this study, researchers surveyed 100 women with PCOD or PCOS and found no statistical correlation between the diagnosis and common symptoms like irregular menstruation or infertility, suggesting a need for further research with larger samples.
1 citations
,
September 2013 in “Revue d'Épidémiologie et de Santé Publique” Higher unemployment rates are linked to increased suicide rates, especially in men aged 25-49 in France.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that specific immune cell phenotypes, particularly CD25 on CD4 Treg cells, were causally linked to androgenic alopecia, suggesting potential targets for immune-based therapies.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case report discusses a patient with VHL-associated paraganglioma, highlighting the importance of genetic testing and monitoring in those with VHL disease, due to high mutation penetrance and associated risks.
23 citations
,
April 2017 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the importance of recognizing and treating psychiatric conditions in dermatology patients, offering practical recommendations for dermatologists to manage psychocutaneous diseases effectively, but reports no new clinical results.
1 citations
,
January 2017 in “Expert opinion on orphan drugs” This study reviews current systemic treatments for hidradenitis suppurativa, highlighting traditional methods and new options like biological agents, and suggests that pharmacological therapies show promise, particularly for non-advanced cases, despite the disease's complex etiology involving factors such as genetics and inflammation.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This review highlights the significant psychosocial impact of alopecia areata on children and adolescents, affecting self-esteem, relationships, academic performance, and the well-being of their families.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.
October 2024 in “Irish Journal of Medical Science (1971 -)” In this study, TENS of the T6 dermatome over a longer term was explored for its effects on weight, blood pressure, heart rate, and appetite-regulating hormones in obese subjects with moderate obstructive sleep apnea; however, results are not reported in the abstract.
June 2023 in “Dermatology and therapy” This literature review highlights challenges in managing alopecia areata in the Middle East and Africa, noting significant regional gaps in data, treatment guidelines, and public awareness that impede patient care and emphasize the need for improved support and resources.
June 1996 in “Irish Journal of Medical Science (1971 -)” This study found a statistically significant increase in glycosylated hemoglobins among patients with adult-acquired panhypopituitarism undergoing long-term GH replacement therapy, with two developing diabetes requiring treatment.
47 citations
,
December 2019 in “Frontiers in immunology” This study identified a novel G207E STING mutation associated with severe inflammatory symptoms and suggested that common polymorphisms in TMEM173 and IFIH1 may modify the phenotype in affected individuals.
1 citations
,
August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that a novel gain-of-function mutation in TMEM173, combined with polymorphisms in TMEM173 and IFIH1, results in a distinct clinical phenotype with features of SAVI, including alopecia and photosensitivity.
research 22
December 2023 in “Psychiatry Neurology and Medical Psychology” Alopecia can lead to mental health issues, so treatment should address both skin and emotional health.
32 citations
,
December 2018 in “Cytokine” This review discusses the involvement of type I interferons in skin autoimmune and inflammatory diseases but reports no new clinical results.
2 citations
,
January 2021 in “Scandinavian Journal of Child and Adolescent Psychiatry and Psychology” This study found that children and adolescents with dermatological disorders had significantly higher rates of psychiatric comorbidity, including mood and anxiety disorders, compared to healthy controls.
10 citations
,
January 2023 in “Journal of the European Academy of Dermatology and Venereology” This review highlights the significant negative impact of alopecia areata on quality of life, mental health, and work, calling for individualized approaches and effective treatments to mitigate these effects.
40 citations
,
September 2019 in “World journal of clinical cases” In this case report, an 86-year-old man experienced new hair growth and color change in alopecia areata after receiving fecal microbiota transplantation for noninfectious diarrhea.
4 citations
,
October 2022 in “Genes” This review discusses the role of cutaneous and intestinal microbiota in the development of alopecia areata, summarizing current literature without reporting new clinical results.
2 citations
,
February 2024 in “International journal of molecular sciences” This review explores the connection between the gut-skin axis and the development of dermatological conditions like atopic dermatitis, psoriasis, alopecia areata, and acne, and discusses the potential of probiotics in reshaping the microbiome to alleviate these skin issues.
November 2016 in “Regenerative Medicine” This article compiles stem cell and regenerative medicine developments from industry press releases in September 2016, reporting no new study results.
91 citations
,
August 2019 in “Frontiers in Microbiology” This study found that the RpoN/RpoS pathway regulates gene expression in Borrelia burgdorferi, influencing its ability to persist in mammals and adapt to different hosts.
18 citations
,
July 2024 in “Frontiers in Immunology” This review explores the complex relationships between ferroptosis, anastasis, and chemoresistance in cancer therapy, highlighting the potential of combining ferroptosis with immunotherapy to overcome resistance and improve personalized cancer treatments.
12 citations
,
February 2010 in “Tetrahedron Letters” This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.